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Event

Neuro Epilepsy Lecture Series - Red and Green Spikes Revisited: Is the Concept Still Valid?

Thursday, September 19, 2024 16:00to17:00
Montreal Neurological Institute de Grandpre Communications Centre, 3801 rue University, Montreal, QC, H3A 2B4, CA

The 2024-2025 Neuro Epilepsy Lecture Series will include eight lectures covering hot topics in basic and clinical epilepsy research. Speakers will include distinguished leaders and rising stars, with the goal of bridging basic research and clinical perspectives.


To attend in person,

To watch the livestream,


Birgit Frauscher, PhD

Professor, Department of Neurology, Duke University School of Medicine

Host: Boris Bernhardt

Talk Title:ÌýRed and Green Spikes Revisited: Is the Concept Still Valid?

Abstract: Several decades ago, Penfield and Jasper introduced the concept of 'red' and 'green' spikes in epilepsy presurgical evaluation. This concept suggests that there are two distinct spike subtypes with different generation mechanisms and contrasting implications for clinical management. This talk will revisit this concept from various perspectives: it will review the latest evidence indicating that not all spikes are equal, with some subtypes being more critical for epileptogenicity than others. It will also discuss how spikes can be used to address the longstanding issue of limited sampling in invasive intracranial EEG. Finally, the talk will challenge the current paradigm that focuses primarily on the recording of seizures, highlighting how spikes and other seizure-independent biomarkers can indeed be valuable for epilepsy presurgical evaluation.


These seminar series are made possible through the sponsorship of:

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The Neuro logoÌýMcGill logo

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The Neuro (Montreal Neurological Institute-Hospital)Ìýis a bilingual academic healthcare institution. We are aÌýMcGill research and teaching institute; delivering high-quality patient care, as part of the Neuroscience Mission of the McGill University Health Centre.ÌýWe areÌýproud to be a Killam Institution, supported by the Killam Trusts.

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