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Killam Seminar Series: Encoding Dopamine Signals in Striatal Circuits

Mardi, 17 septembre, 2024 16:00à17:00
Montreal Neurological Institute de Grandpre Communications Centre, 3801 rue University, Montreal, QC, H3A 2B4, CA

Grâce à la générosité des fiducies Killam, Le Neuro convoque lors d’une série de séminaires des conférenciers d’exception dont les travaux passionnent ses chercheurs et ceux de l’Université McGill.Ìý


Pour assister en personne,Ìý

Pour regarder via Vimeo,Ìý


Christopher Ford

Professeur, Département de pharmacologie, Université du Colorado.

±áô³Ù±ð:Ìýausten.milnerwood [at] mcgill.ca (Austen Milnerwood)

Abstract:ÌýFord's lab examines how neuromodulators are encoded in the mesolimbic and nigrostriatal systems and how circuit dysfunctions in these areas contribute to neurological and psychiatric disorders. Dopamine, acetylcholine and serotonin play key roles in the basal ganglia and nucleus accumbens, controlling a variety of motivated behaviors including decision-making, action selection, motor skill learning, habit formation and reward processing. The lab uses a combination of electrophysiology, 2-photon imaging, optogenetics, genetically encoded optical sensors, electrochemistry, in vivo fiber photometry and behavioral approaches to study how transmission mediated by these neuromodulators are encoded within mesolimbic and nigrostriatal circuits. By identifying the mechanisms regulating signaling Ford's lab aims to identify the disruptions in these systems that underlie psychiatric disorders such as drug addiction and schizophrenia and neurological disorders such as Parkinson’s disease.

Le NeuroÌýMcGill

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Le Neuro (L'Institut-Hôpital neurologiqueÌýde Montréal) - un institut de recherche et d’enseignement bilingue de McGill, qui offre des soins de haut calibre aux patients - est la pierre angulaire de la Mission en neurosciences du Centre universitaire de santé McGill. Nous sommes fiers d’être une institution Killam, soutenue par les fiducies Killam.

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