Killam Seminar Series: Single-Cell Approaches to Studying Connectivity and Neuronal States During Fear Learning
Gr芒ce 脿 la g茅n茅rosit茅 des fiducies Killam, Le Neuro convoque lors d鈥檜ne s茅rie de s茅minaires des conf茅renciers d鈥檈xception dont les travaux passionnent ses chercheurs et ceux de l鈥橴niversit茅 McGill.听
Pour assister en personne,听
Pour regarder via Vimeo,听
Amit Zeisel
Professeur adjoint, 贵补肠耻濒迟茅 de biotechnologie et de g茅nie alimentaire, Institut de nanotechnologie Russell Berrie, Isra毛l.
贬么迟别:听j-francois.poulin [at] mcgill.ca (Jean-Fran莽ois Poulin)
Abstract:听In this seminar, Amit Zeisel will cover two topics investigated in his lab. The first part involves the generation of a comprehensive cellular taxonomy of the mouse amygdala. By employing single-cell RNA sequencing, his team has identified distinct neuronal subtypes and their specific transcriptional profiles. This work enables the mapping of cell-type-specific transcriptional responses during the consolidation of the fear conditioning process, providing insights into the molecular underpinnings of fear memory formation. In the second part, Amit Zeisel will introduce methods for constructing brain-wide monosynaptic connectivity maps. Utilizing a barcoded rabies virus, his lab has developed a novel approach to trace and map the synaptic connections of individual neurons across the brain.
