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Major Pharmacology (65 credits)

Note: This is the 2011–2012 edition of the eCalendar. Update the year in your browser's URL bar for the most recent version of this page, or click here to jump to the newest eCalendar.

Offered by: Pharmacology and Therapeutics     Degree: Bachelor of Science

Program Requirements

Revision, August 2011. Start of revision. This program incorporates extensive studies in Pharmacology with a strong component of related biomedical sciences, providing a solid preparation for employment opportunities or for entry into graduate or professional training programs. Students must consult an adviser upon entering the program and at the beginning of U2 to verify courses and progress. Additional consultation at regular intervals is encouraged.

U1 Required Courses (22 credits)

  • BIOL 200 Molecular Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression.

    Terms: Fall 2011

    Instructors: Bureau, Thomas E; Roy, Richard D W; Fagotto, Francesco; Zetka, Monique (Fall)

    • Fall

    • 3 hours lecture, 1 hour optional tutorial

    • Prerequisite: BIOL 112 or equivalent

    • Corequisite: CHEM 212 or equivalent

  • BIOL 202 Basic Genetics (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Introduction to basic principles, and to modern advances, problems and applications in the genetics of higher and lower organisms with examples representative of the biological sciences.

    Terms: Winter 2012, Summer 2012

    Instructors: Western, Tamara; Chevrette, Mario; Hendry, Andrew (Winter) Dankort, David; Hipfner, David (Summer)

    • Winter, Summer

    • 3 hours lecture, 1 hour optional tutorial

    • Prerequisite: BIOL 200.

    • Restriction: Not open to students who have taken or are taking CELL 204.

  • CHEM 212 Introductory Organic Chemistry 1 (4 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : A survey of reactions of aliphatic and aromatic compounds including modern concepts of bonding, mechanisms, conformational analysis, and stereochemistry.

    Terms: Fall 2011, Winter 2012, Summer 2012

    Instructors: Daoust, Michel; Sewall, Samuel Lewis; Gauthier, Jean-Marc; Tsantrizos, Youla S (Fall) Harpp, David Noble; Schirrmacher, Ralf; Daoust, Michel; Sewall, Samuel Lewis; Gauthier, Jean-Marc (Winter) Fenster, Ariel; Daoust, Michel (Summer)

    • Fall, Winter, Summer

    • Prerequisite: CHEM 110 or equivalent.

    • Corequisite: CHEM 120 or equivalent.

    • Restriction: Not open to students who are taking or have taken CHEM 211 or equivalent

    • Each lab section is limited enrolment

    • Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page ().

  • CHEM 222 Introductory Organic Chemistry 2 (4 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Modern spectroscopic techniques for structure determination. The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. Special topics.

    Terms: Fall 2011, Winter 2012, Summer 2012

    Instructors: Daoust, Michel; Sewall, Samuel Lewis; Gauthier, Jean-Marc; Harpp, David Noble; Perepichka, Dmytro (Fall) Daoust, Michel; Sewall, Samuel Lewis; Gauthier, Jean-Marc; Auclair, Karine (Winter) Daoust, Michel; Schwarcz, Joseph A (Summer)

    • Fall, Winter

    • Prerequisite: CHEM 212 or equivalent.

    • Restriction: Not open to students who have taken an equivalent Organic 2 at CEGEP (see McGill University Basic Math and Sciences Equivalence Table at ) or who have or are taking CHEM 234.

  • PHGY 209 Mammalian Physiology 1 (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.

    Terms: Fall 2011

    Instructors: Wechsler, Ann; Gold, Phil; Ragsdale, David S (Fall)

  • PHGY 210 Mammalian Physiology 2 (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.

    Terms: Winter 2012

    Instructors: White, John H; Wechsler, Ann; Takano, Tomoko (Winter)

  • PHGY 212 Introductory Physiology Laboratory 1 (1 credit)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Exercises illustrating fundamental principles in physiology: Biological Signals Acquisitions, Blood, Immunology, Neurophysiology, Neuromuscular Physiology.

    Terms: Fall 2011

    Instructors: Martinez Trujillo, Julio; Glavinovic, Mladen I; Krnjevic, Kresimir; Farookhi, Riaz; Bernard, Nicole F (Fall)

    • (One 3-hour lab and one 1-hour lecture every second week.)

    • Corequisite: PHGY 209.

    • Restrictions: Required for Physiology students enrolled in PHGY 209. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.

    • Note: For students in a Physiology program, PHGY 212 should be taken concurrently with PHGY 209.

  • PHGY 213 Introductory Physiology Laboratory 2 (1 credit)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Exercises illustrating fundamental principles in physiology: Central Nervous System, Cardiovascular, Respiration, Exercise Physiology, Molecular Endocrinology.

    Terms: Winter 2012

    Instructors: Guevara, Michael R; Glavinovic, Mladen I; Krnjevic, Kresimir; Watt, Douglas; Mortola, Jacopo (Winter)

    • (One 3-hour lab and one 1-hour lecture every second week.)

    • Prerequisite: PHGY 212

    • Corequisite: PHGY 210.

    • Restrictions: Required for Physiology students enrolled in PHGY 210. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.

    • Note: For students in a Physiology program, PHGY 213 should be taken concurrently with PHGY 210.

U2 Required Courses (16 credits)

  • BIOC 311 Metabolic Biochemistry (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : The generation of metabolic energy in higher organisms with an emphasis on its regulation at the molecular, cellular and organ level. Chemical concepts and mechanisms of enzymatic catalysis are also emphasized. Included: selected topics in carbohydrate, lipid and nitrogen metabolism; complex lipids and biological membranes; hormonal signal transduction.

    Terms: Fall 2011

    Instructors: St-Pierre, Julie; Dostie, Josee; Nagar, Bhushan (Fall)

  • BIOL 301 Cell and Molecular Laboratory (4 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : An introduction to laboratory techniques with a focus on methods used to investigate fundamental questions in modern cell and molecular biology. Techniques including gene cloning, DNA and protein isolation and manipulation are covered, along with functional analysis of genes and proteins, basic bioinformatics, and computer-based experimental design and data analysis.

    Terms: Fall 2011, Winter 2012

    Instructors: Moon, Nam Sung; Dent, Joseph Alan; Zheng, Huanquan (Fall) Moon, Nam Sung; Harrison, Paul; Zheng, Huanquan (Winter)

    • Fall or Winter

    • 1 hour lecture and one 6-hour laboratory

    • Prerequisites: PHYS 102 or PHYS 142, BIOL 200, BIOL 201 or ANAT/BIOC 212, and BIOL 202. BIOL 206 recommended.

    • Restrictions: Not open to students who have taken or are taking BIOC 300. Requires departmental approval.

    • For approval email anne-marie.sdicu [at] mcgill.ca. Specify your ID number as well as the term and lab day.

  • PHAR 300 Drug Action (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Principles of pharmacology and toxicology. Frequently encountered drugs will be used as a focus to illustrate sites and mechanisms of action, distribution, metabolism, elimination and adverse side effects.

    Terms: Fall 2011

    Instructors: Zorychta, Edith (Fall)

  • PHAR 301 Drugs and Disease (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This course further explores the basic principles of pharmacology as illustrated by drugs used in the treatment of disease. Emphasis is placed on drugs used for diseases prevalent in North America.

    Terms: Winter 2012

    Instructors: Delbès, Géraldine; Clarke, Paul; Bowie, Derek (Winter)

    • Winter

    • Prerequisite: PHAR 300 or permission of instructor.

  • PHAR 303 Principles of Toxicology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth.

    Terms: Winter 2012

    Instructors: Culty, Martine; Zorychta, Edith; Delbès, Géraldine (Winter)

U3 Required Courses (12 credits)

  • PHAR 503 Drug Design and Development 1 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Chemistry, mechanisms of action and steps in drug development.

    Terms: Fall 2011

    Instructors: Maysinger, Dusica (Fall)

  • PHAR 558 Pharmacology Selected Topics (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Changing nature of selected drug targets in light of advances in studying proteins in their native cellular milieu, in the context of intact tissues, organs and whole animals, highlighting several conceptual advances in pharmacological theory with bearing on how drug targets are viewed and characterized.

    Terms: Winter 2012

    Instructors: Hebert, Terence; McKinney, R. Anne (Winter)

    • Prerequisite: PHAR 562 or permission of the instructor.

    • Corequisite: PHAR 563 or permission of the instructor.

  • PHAR 562 General Pharmacology 1 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Topics in pharmacology with an emphasis on molecular aspects and the nervous system; topics include molecular mechanisms of drug-action, cellular targets and rationale for therapeutics.

    Terms: Fall 2011

    Instructors: Almazan, Guillermina (Fall)

    • Fall

    • Prerequisite: PHAR 301.

    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.

  • PHAR 563 General Pharmacology 2 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Selected topics in pharmacology of the endocrine, metabolic, and cardiovascular systems. Additional topics include: pharmacogenetics/pharmacogenomics, chronopharmacology, molecular structure in pharmacology, epigenetic targets in cancer chemotherapy, and stem cell therapies.

    Terms: Winter 2012

    Instructors: Bernard, Daniel (Winter)

    • Winter

    • Prerequisite: PHAR 301.

    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.

Complementary Courses (15 credits)

15 credits selected as follows:

3 credits selected from:

  • ANAT 212 Molecular Mechanisms of Cell Function (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.

    Terms: Winter 2012

    Instructors: Pause, Arnim; Bouchard, Maxime; Young, Jason (Winter)

  • BIOC 212 Molecular Mechanisms of Cell Function (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.

    Terms: Winter 2012

    Instructors: Pause, Arnim; Bouchard, Maxime; Young, Jason (Winter)

    • Winter

    • Prerequisite: BIOL 200

    • Restrictions: A non-terminal course intended to be followed by BIOC 311; BIOC 312 in the U2 year. Not open to students who have taken or are taking BIOL 201 or ANAT 212.

  • BIOL 201 Cell Biology and Metabolism (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : This course introduces the student to our modern understanding of cells and how they work. Major topics to be covered include: photosynthesis, energy metabolism and metabolic integration; plasma membrane including secretion, endocytosis and contact mediated interactions between cells; cytoskeleton including cell and organelle movement; the nervous system; hormone signaling; the cell cycle.

    Terms: Winter 2012

    Instructors: Brouhard, Gary; Roy, Richard D W; Western, Tamara (Winter)

    • Winter

    • 3 hours lecture, 1 hour optional tutorial

    • Prerequisite: BIOL 200.

    • Restriction: Not open to students who have taken or are taking ANAT 212 or BIOC 212

3 credits selected from:

3 credits selected from:

  • BIOL 373 Biometry (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Elementary statistical methods in biology. Introduction to the analysis of biological data with emphasis on the assumptions behind statistical tests and models. Use of statistical techniques typically available on computer packages.

    Terms: Fall 2011

    Instructors: Leung, Brian (Fall)

    • Fall

    • 2 hours lecture and 2 hours laboratory

    • Prerequisite: MATH 112 or equivalent

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.

  • MATH 203 Principles of Statistics 1 (3 credits)

    Offered by: Mathematics and Statistics (Faculty of Science)

    Overview

    Mathematics & Statistics (Sci) : Examples of statistical data and the use of graphical means to summarize the data. Basic distributions arising in the natural and behavioural sciences. The logical meaning of a test of significance and a confidence interval. Tests of significance and confidence intervals in the one and two sample setting (means, variances and proportions).

    Terms: Fall 2011, Winter 2012, Summer 2012

    Instructors: Khalili Mahmoudabadi, Abbas; Genest, Christian (Fall) Wolfson, David B (Winter) Hundemer, Axel W (Summer)

    • No calculus prerequisites

    • Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps.

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Students should consult for information regarding transfer credits for this course.

  • PSYC 204 Introduction to Psychological Statistics (3 credits)

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : The statistical analysis of research data; frequency distributions; graphic representation; measures of central tendency and variability; elementary sampling theory and tests of significance.

    Terms: Fall 2011, Winter 2012, Summer 2012

    Instructors: Amsel, Rhonda N (Fall) Ostry, David J (Winter) Zangenehpour, Shahin (Summer)

    • Fall and Winter

    • Restriction: Not open to students who have passed a CEGEP statistics course(s) with a minimum grade of 75%: Mathematics 201-307 or 201-337 or equivalent or the combination of Quantitative Methods 300 with Mathematics 300

    • This course is a prerequisite for PSYC 305, PSYC 406, PSYC 310, PSYC 336

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.

6 credits selected from the following upper-level science courses:

Committee approval is required to substitute an upper-level science course not in the list below.

PHAR 599D1 and PHAR 599D2 are taken together.

* Note: Students may take either ANAT 458 or BIOC 458.
** Note: Students may take either CHEM 504 or PHAR 504.

  • ANAT 321 Circuitry of the Human Brain (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course explores the functional organization of the human brain and spinal cord. The course focuses on how neuronal systems are designed to subserve specific motor, sensory, and cognitive operations.

    Terms: Fall 2011

    Instructors: Brawer, James; David, Samuel (Fall)

    • Fall

    • 2 hour lectures, 2 hours laboratory/tutorial

    • Prerequisites: ANAT/BIOC 212 or BIOL 201; and one of PHGY 209, NSCI 200 or PSYC 211; or permission of instructor

    • Restriction: Open to U3 students only

  • ANAT 365 Cellular Trafficking (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An intensive study of the processes of protein secretion and cell membrane biogenesis. Emphasis on morphological aspects of the above processes, and on the major techniques which have provided experimental evidence, namely, subcellular fractionation, cytochemistry and quantitative electron microscope radioautography.

    Terms: Fall 2011

    Instructors: Bedford, Fiona Kay; McBride, Heidi; McPherson, Peter Scott (Fall)

  • ANAT 458 Membranes and Cellular Signaling (3 credits) *

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.

    Terms: Winter 2012

    Instructors: Silvius, John R; Lamarche, Nathalie; Bedford, Fiona Kay (Winter)

  • BIOC 312 Biochemistry of Macromolecules (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Gene expression from the start of transcription to the synthesis of proteins, their modifications and degradation. Topics covered: purine and pyrimidine metabolism; transcription and its regulation; mRNA processing; translation; targeting of proteins to specific cellular sites; protein glycosylation; protein phosphorylation; protein turn-over; programmed cell death (apoptosis).

    Terms: Winter 2012

    Instructors: Nepveu, Alain; Sonenberg, Nahum; Shore, Gordon C (Winter)

  • BIOC 450 Protein Structure and Function (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Primary, secondary, tertiary and quaternary structure of enzymes. Active site mapping and site-specific mutagenesis of enzymes. Enzyme kinetics and mechanisms of catalysis. Multienzyme complexes.

    Terms: Fall 2011

    Instructors: Nagar, Bhushan; Schmeing, Thomas Martin; Gotte, Matthias (Fall)

    • Fall

    • Prerequisites: BIOC 311, BIOC 312 and/or sufficient organic chemistry.

    • Restriction: Intended primarily for students at the U3 level

  • BIOC 454 Nucleic Acids (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : RNA processing, localization and stability. RNAi mechanisms, regulation and applications. Regulation of DNA replication. Genomics: human genome sequence, regulation and organization. DNA repair mechanisms. Special topics on transgenics, genetic diseases and cancer.

    Terms: Fall 2011

    Instructors: Dostie, Josee; Teodoro, Jose Guerreiro; Gallouzi, Imed Eddine (Fall)

  • BIOC 458 Membranes and Cellular Signaling (3 credits) *

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.

    Terms: Winter 2012

    Instructors: Silvius, John R; Lamarche, Nathalie; Bedford, Fiona Kay (Winter)

  • BIOL 300 Molecular Biology of the Gene (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction.

    Terms: Fall 2011

    Instructors: Schöck, Frieder; Nilson, Laura; Rocheleau, Christian (Fall)

  • BIOL 303 Developmental Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A consideration of the fundamental processes and principles operating during embryogenesis. Experimental analyses at the molecular, cellular, and organismal levels will be presented and discussed to provide an overall appreciation of developmental phenomena.

    Terms: Winter 2012

    Instructors: Nilson, Laura; Rao, Yong; Dufort, Daniel (Winter)

  • BIOL 306 Neural Basis of Behaviour (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Neural mechanisms of animal behaviour; neuroethology; cellular neurophysiology, integrative networks within nervous systems; neural control of movement; processing of sensory information.

    Terms: Fall 2011

    Instructors: Pollack, Gerald; Dent, Joseph Alan; Krahe, Rudiger (Fall)

  • BIOL 314 Molecular Biology of Oncogenes (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : The genes that cause cancer are altered versions of genes present in normal cells. The origins of these oncogenes, their genetic structure, regulation, and the biochemical properties of the oncogene-encoded proteins will be analyzed in an attempt to understand the origins of human and animal cancers.

    Terms: Fall 2011

    Instructors: Majewska, Loydie; Jabado, Nada; Duchaine, Thomas (Fall)

  • BIOT 505 Selected Topics in Biotechnology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biotechnology : Current methods and recent advances in biological, medical, agricultural and engineering aspects of biotechnology will be described and discussed. An extensive reading list will complement the lecture material.

    Terms: Fall 2011

    Instructors: Vogel, Jacalyn (Fall)

    • Fall

    • Restriction: U3 students

  • CHEM 302 Introductory Organic Chemistry 3 (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Topics covered may include the following: Aromatic compounds, heterocyclic chemistry, sulfur and phosphorus chemistry, organosulfur and organophosphorus compounds, and biomolecules such as lipids, carbohydrates, amino acids, polypeptides, DNA and RNA.

    Terms: Fall 2011, Winter 2012

    Instructors: Damha, Masad J (Fall) Sleiman, Hanadi (Winter)

    • Fall, Winter

    • Prerequisites: BIOL 112, CHEM 222, or permission of the instructor.

  • CHEM 502 Advanced Bio-Organic Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : This course will cover biologically relevant molecules, particularly nucleic acids, proteins, and their building blocks. In each case, synthesis and biological functions will be discussed. The topics include synthesis of oligonucleotides and peptides; chemistry of phosphates; enzyme structure and function; coenzymes, and enzyme catalysis; polyketides; antiviral and anticancer agents.

    Terms: Winter 2012

    Instructors: Auclair, Karine; Damha, Masad J (Winter)

    • Winter

    • Prerequisite: CHEM 302

    • Restriction: Not open to students who have taken CHEM 402.

  • CHEM 504 Drug Design and Development 2 (3 credits) **

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Computational methods used in drug design and discovery including QSAR, docking/scoring, molecular mechanics and molecular dynamics, QM/MM, library profiling and library design.

    Terms: This course is not scheduled for the 2011-2012 academic year.

    Instructors: There are no professors associated with this course for the 2011-2012 academic year.

    • Winter
    • Prerequisite: CHEM 503 and permission of instructor
    • Restriction: U3 and graduate students. Students can register only with permission of coordinators
  • EXMD 504 Biology of Cancer (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy.

    Terms: Fall 2011

    Instructors: Thomson, David M P (Fall)

    • Fall

    • Prerequisite (Undergraduate): A good knowledge of biology at the cellular and molecular level. Open to U3 and graduate students only

  • EXMD 511 Joint Venturing with Industry (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Using problem-based learning, the course examines the various business interactions between researchers and their business partners in support and development of research into commercial endeavours using models such as venture capital, business partnerships, or grants-in-aid.

    Terms: Winter 2012

    Instructors: Bennett, Hugh P J; Clarke, K Steven (Winter)

    • Winter

    • Offered in conjunction with the Centre for Continuing Education

  • MIMM 314 Immunology (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : An introduction to the immune system, antigens, antibodies and lymphocytes. The course will cover the cellular and molecular basis of lymphocyte development and mechanisms of lymphocyte activation in immune responses.

    Terms: Winter 2012

    Instructors: Piccirillo, Ciriaco; Alizadehfar, Reza; Fournier, Sylvie (Winter)

  • MIMM 387 The Business of Science (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : The ability to select and manipulate genetic material has lead to unprecedented interest in the industrial applications of procaryotic and eucaryotic cells. Beginning in the 1970s the introduction of and subsequent refinements to recombinant DNA technology and hybridoma technology transformed the horizons of the biopharmaceutical world. This course will highlight the important events that link basic research to clinical/commercial application of new drugs and chemicals.

    Terms: Winter 2012

    Instructors: Murgita, Robert A; Bar-Or, Amit; Khoury, Lara (Winter)

    • Winter

    • Prerequisite: At least one 200-level course in a biological or biomedical discipline or permission of instructor

  • MIMM 414 Advanced Immunology (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : An advanced course serving as a logical extension of MIMM 314. The course will integrate molecular, cellular and biochemical events involved in the ontogeny of the lymphoid system and its activation in the immune response. The course will provide the student with an up-to-date understanding of a rapidly moving field.

    Terms: Fall 2011

    Instructors: Fournier, Sylvie; Olivier, Martin; Arbour, Nathalie (Fall)

    • Fall

    • 3 hour lecture

    • Prerequisite: MIMM 314

  • NEUR 310 Cellular Neurobiology (3 credits)

    Offered by: Neurology and Neurosurgery (Faculty of Science)

    Overview

    Neurology and Neurosurgery : A survey of the functional organization of nerve cells, signalling in the nervous system, and principles of neural development. Topics include cell polarity, neurotransmitters, neurotrophins, receptors and second messengers, cell lineage, guidance of axon outgrowth, and nerve regeneration. Emphasis will be placed on analysis of neurons at the molecular level.

    Terms: Winter 2012

    Instructors: Cloutier, Jean-Francois; Ragsdale, David S; Kennedy, Timothy E (Winter)

  • PATH 300 Human Disease (3 credits)

    Offered by: Pathology (Faculty of Science)

    Overview

    Pathology : Provides a fundamental understanding of the diseases prevalent in North America, for upper level students in the biological sciences. Includes: general responses of cells and organ systems to injury; assessment of individual diseases by relating the causes, symptoms, diagnosis, treatment and prevention to the primary biological abnormalities in each disorder.

    Terms: Winter 2012

    Instructors: Zorychta, Edith; Richardson, John B (Winter)

  • PHAR 504 Drug Design and Development 2 (3 credits) **

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Possible untoward effects and reasons for drug (dis)approval.

    Terms: Winter 2012

    Instructors: Maysinger, Dusica (Winter)

    • Winter

    • Prerequisites: PHAR 503, or permission of coordinator

    • Restriction: U3 and graduate students. Students can register only with permission of coordinators.

  • PHAR 599D1 Pharmacology Research Project (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Mechanisms involved in different pathologies and drug actions.

    Terms: Fall 2011

    Instructors: McKinney, R. Anne; Maysinger, Dusica (Fall)

    • Fall

    • Minimum of 9 hours/week to be spent in the lab and/or library.

    • Pre-/Co-requisite: PHAR 562 and PHAR 563.

    • Restriction: U3 students with permission of instructors; students should consult instructors 3 - 4 weeks before registration.

    • Students must register for both PHAR 599D1 and PHAR 599D2.

    • No credit will be given for this course unless both PHAR 599D1 and PHAR 599D2 are successfully completed in consecutive terms

    • PHAR 599D1 and PHAR 599D2 together are equivalent to PHAR 599

    • Please see regulations concerning Project Courses

  • PHAR 599D2 Pharmacology Research Project (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : See PHAR 599D1 for course description.

    Terms: Winter 2012

    Instructors: Maysinger, Dusica; McKinney, R. Anne (Winter)

  • PHGY 311 Channels, Synapses & Hormones (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system.

    Terms: Fall 2011

    Instructors: Cooper, Ellis; Farookhi, Riaz; Haghighi, Ali (Fall)

    • Fall

    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term

    • Prerequisite: PHGY 209 or permission of the instructor.

  • PHGY 312 Respiratory, Renal, & Cardiovascular Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level.

    Terms: Winter 2012

    Instructors: Hanrahan, John W; Mortola, Jacopo; Shrier, Alvin (Winter)

    • Winter

    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term

    • Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor

  • PHGY 313 Blood, Gastrointestinal, & Immune Systems Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology.

    Terms: Winter 2012

    Instructors: Martinez Trujillo, Julio; Blank, Volker Manfred; Ponka, Premysl (Winter)

    • Winter

    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term

    • Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor

  • PHGY 314 Integrative Neuroscience (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours.

    Terms: Fall 2011

    Instructors: Cullen, Kathleen E; Martinez Trujillo, Julio; Pack, Christopher (Fall)

    • Fall

    • 3 hours of lectures per week

    • Prerequisites: PHGY 209

  • PHGY 520 Ion Channels (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : A discussion of the principal theories and interesting new developments in the study of ion channels. Based on a textbook, computer exercises and critical reading and presentation of research papers. Topics include: Properties of voltage-and ligand-gated channels, single channel analysis, structure and function of ion channels.

    Terms: This course is not scheduled for the 2011-2012 academic year.

    Instructors: There are no professors associated with this course for the 2011-2012 academic year.

    • Winter
    • Offered in even numbered years
    • 1 1/2 hour lecture, 1 1/2 hour seminar
    • Prerequisite: PHGY 311
    • Priority to Graduate and Honours students; others by permission of instructors.
  • PSYC 311 Human Cognition and the Brain (3 credits)

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : The course is an introduction to the field studying how human cognitive processes, such as perception, attention, language, learning and memory, planning and organization, are related to brain processes. The material covered is primarily based on studies of the effects of different brain lesions on cognition and studies of brain activity in relation to cognitive processes with modern functional neuroimaging methods.

    Terms: Fall 2011, Summer 2012

    Instructors: Petrides, Michalakis (Fall) Petrides, Michalakis (Summer)

    • Fall

    • 2 lectures; 1 conference

  • PSYT 455 Neurochemistry (3 credits)

    Offered by: Psychiatry (Faculty of Science)

    Overview

    Psychiatry : Covers biochemical mechanisms underlying central nervous system function. Introduces basic neuroanatomy, CNS cell types and morphology, neuronal excitability, chemically mediated transmission, glial function. Biochemistry of specific neurotransmitters, endocrine effects on brain, brain energy metabolism and cerebral ischemia (stroke). With examples, where relevant, of biochemical processes disrupted in human CNS disease.

    Terms: Winter 2012

    Instructors: Flores Parkman, Ana Cecilia; Mechawar, Naguib; Wong, Tak Pan (Winter)

    • Winter

    • Prerequisites: BIOC 311, BIOC 312 or permission of instructor

    • Restriction: Not open to students who have taken BIOC 455

Revision, August 2011. End of revision.

Faculty of Science—2011-2012 (last updated Jan. 26, 2012) (disclaimer)
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