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Program Requirements
Revision, April 2018. Start of revision.
IHI is a 75-credit program involving the Departments of Biochemistry; Microbiology and Immunology; and Physiology, and incorporates elements from each of these disciplines. Immunology is a key area of biomedical research and is critical to our understanding of the patho-physiology of many immune-mediated diseases. This program provides an excellent foundation for students interested in pursuing a career in biomedical research and/or medicine.
The program consists of 48 required credits of basic science courses,covering cell and molecular biology; microbiology and immunology; biochemistry; and physiology. There are also 27 complementary credits which allow for specialization in immunology and related disciplines. To graduate from IHI, students must have a minimum CGPA of 3.30 and pass five immunology courses (MIMM 214, MIMM 314, MIMM 414, PHGY 419D1 and D2, PHGY 513, and one of BIOC 503, MIMM 509, PHGY 531) with a minimum grade of B.
Required Courses (48 credits)
U1 Required Courses
20 credits selected as follows:
* Students select either BIOC 212 or BIOL 201.
** Students select either PHGY 209 or MIMM 211.
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BIOC 212 Molecular Mechanisms of Cell Function (3 credits) *
Overview
Biochemistry : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.
Terms: Winter 2019
Instructors: Pause, Arnim; Denis, Maxime; Bouchard, Maxime; Young, Jason; Reinhardt, Dieter; Duchaine, Thomas (Winter)
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BIOL 200 Molecular Biology (3 credits)
Overview
Biology (Sci) : The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression.
Terms: Fall 2018
Instructors: Zetka, Monique; Hastings, Kenneth E M; Reyes Lamothe, Rodrigo; Lasko, Paul; Hendricks, Shelton (Fall)
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BIOL 201 Cell Biology and Metabolism (3 credits) *
Overview
Biology (Sci) : This course introduces the student to our modern understanding of cells and how they work. Major topics to be covered include: photosynthesis, energy metabolism and metabolic integration; plasma membrane including secretion, endocytosis and contact mediated interactions between cells; cytoskeleton including cell and organelle movement; the nervous system; hormone signaling; the cell cycle.
Terms: Winter 2019
Instructors: Brouhard, Gary (Winter)
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CHEM 212 Introductory Organic Chemistry 1 (4 credits)
Overview
Chemistry : A survey of reactions of aliphatic and aromatic compounds including modern concepts of bonding, mechanisms, conformational analysis, and stereochemistry.
Terms: Fall 2018, Winter 2019, Summer 2019
Instructors: Pavelka, Laura; Vlaho, Danielle; Daoust, Michel; Gauthier, Jean-Marc (Fall) Lumb, Jean-Philip; Vlaho, Danielle; Daoust, Michel; Gauthier, Jean-Marc; Huot, Mitchell (Winter) Sirjoosingh, Pallavi; Vlaho, Danielle; Daoust, Michel; Gauthier, Jean-Marc (Summer)
Fall, Winter, Summer
Prerequisite: CHEM 110 or equivalent.
Corequisite: CHEM 120 or equivalent.
Restriction: Not open to students who are taking or have taken CHEM 211 or equivalent
Each lab section is limited enrolment
Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page ().
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CHEM 222 Introductory Organic Chemistry 2 (4 credits)
Overview
Chemistry : Modern spectroscopic techniques for structure determination. The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. Special topics.
Terms: Fall 2018, Winter 2019, Summer 2019
Instructors: Auclair, Karine; Vlaho, Danielle; Daoust, Michel; Gauthier, Jean-Marc (Fall) Pavelka, Laura; Moitessier, Nicolas; Vlaho, Danielle; Daoust, Michel; Gauthier, Jean-Marc; Huot, Mitchell (Winter) Pavelka, Laura; Sirjoosingh, Pallavi; Vlaho, Danielle; Daoust, Michel; Gauthier, Jean-Marc (Summer)
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MIMM 211 Introductory Microbiology (3 credits) **
Overview
Microbiology and Immun (Sci) : A general treatment of microbiology bearing specifically on the biological properties of microorganisms. Emphasis will be on procaryotic cells. Basic principles of microbial genetics are also introduced.
Terms: Fall 2018
Instructors: Cousineau, Benoit; Nguyen, Dao; Matlashewski, Greg J; Turcotte, Bernard; Gruenheid, Samantha; Archambault, Jacques; Maurice, Corinne (Fall)
Fall
3 hours of lecture
Corequisite: BIOL 200
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MIMM 214 Introductory Immunology: Elements of Immunity (3 credits)
Overview
Microbiology and Immun (Sci) : Basic immunology, organs and cells, elements of innate immunity, phagocytes, complement, elements of adaptive immunity, B-cells, T-cells, antigen presenting cells, MHC genes and molecules, antigen processing and presentation, cytokines and chemokines. Emphasis on anatomy and the molecular and cellular players working together as a physiological system to maintain human health.
Terms: Winter 2019
Instructors: Trottier, Claire (Winter)
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PHGY 209 Mammalian Physiology 1 (3 credits) **
Overview
Physiology : Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.
Terms: Fall 2018
Instructors: Vollrath, Melissa; Gold, Phil; Wechsler, Ann; Ragsdale, David S; Shrier, Alvin; Cook, Erik (Fall)
Fall
3 hours lectures weekly
Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent.
Restriction: Not open to students who have taken PHGY 211 or students who are taking and who have taken NSCI 200.
Restriction: For students in the Faculty of Science, and other students by permission of the instructor
U2 Required Courses
13 credits from the following:
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ANAT 261 Introduction to Dynamic Histology (4 credits)
Overview
Anatomy & Cell Biology : An introduction to light and electron microscopic anatomy in which cell and tissue dynamics will be explored in the principal tissues and organs of the body.
Terms: Fall 2018
Instructors: Mandato, Craig A.; Morales, Carlos R (Fall)
Fall
3 hours lectures, 2 hours laboratory
Must be taken in U1 by students in Anatomy and Cell Biology programs
Prerequisite: BIOL 112 or CEGEP equivalent
Restriction: Open to students in biological sciences and others by special permission
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BIOC 311 Metabolic Biochemistry (3 credits)
Overview
Biochemistry : The generation of metabolic energy in higher organisms with an emphasis on its regulation at the molecular, cellular and organ level. Chemical concepts and mechanisms of enzymatic catalysis are also emphasized. Included: selected topics in carbohydrate, lipid and nitrogen metabolism; complex lipids and biological membranes; hormonal signal transduction.
Terms: Fall 2018
Instructors: Denis, Maxime; Giguere, Vincent; Gehring, Kalle Burgess; Kiss, Robert; Huang, Sidong; Akavia, Uri David; Kazak, Lawrence (Fall)
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BIOC 312 Biochemistry of Macromolecules (3 credits)
Overview
Biochemistry : Gene expression from the start of transcription to the synthesis of proteins, their modifications and degradation. Topics covered: purine and pyrimidine metabolism; transcription and its regulation; mRNA processing; translation; targeting of proteins to specific cellular sites; protein glycosylation; protein phosphorylation; protein turn-over; programmed cell death (apoptosis).
Terms: Winter 2019
Instructors: Huang, Sidong; Richard, Stephane; Denis, Maxime; Gallouzi, Imed Eddine; Sonenberg, Nahum; Pelletier, Gerard; Tremblay, Michel; Turcotte, Bernard; Dostie, Josee; Giguere, Vincent (Winter)
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MIMM 314 Intermediate Immunology (3 credits)
Overview
Microbiology and Immun (Sci) : An intermediate-level immunology course covering the cellular and molecular basis of lymphocyte development and activation in immune responses in health and disease.
Terms: Winter 2019
Instructors: Piccirillo, Ciriaco; Fournier, Sylvie; King, Irah (Winter)
Winter
3 hours of lecture
Prerequisite: MIMM 214
U3 Required Courses
15 credits from the following:
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MIMM 414 Advanced Immunology (3 credits)
Overview
Microbiology and Immun (Sci) : An advanced course serving as a logical extension of MIMM 314. The course will integrate molecular, cellular and biochemical events involved in the ontogeny of the lymphoid system and its activation in the immune response. The course will provide the student with an up-to-date understanding of a rapidly moving field.
Terms: Fall 2018
Instructors: Fritz, Jörg; Richer, Martin; Pike, Kelly-Anne (Fall)
Fall
3 hour lecture
Prerequisite: MIMM 314
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PHGY 419D1 Immunology Research Project (4.5 credits)
Overview
Physiology : Individual research projects in immunology under the guidance of staff members in the three participating departments: Physiology, Biochemistry, and Microbiology and Immunology.
Terms: Fall 2018
Instructors: Cohen, Monroe W; Nijnik, Anastasia; Mandl, Judith (Fall)
Fall
15 hours lab/week
Restriction: Enrolment restricted to U3 Interdepartmental Honours Immunology students or permission of instructors
Students must register for both PHGY 419D1 and PHGY 419D2.
No credit will be given for this course unless both PHGY 419D1 and PHGY 419D2 are successfully completed in consecutive terms
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PHGY 419D2 Immunology Research Project (4.5 credits)
Overview
Physiology : See PHGY 419D1 for course description.
Terms: Winter 2019
Instructors: Cohen, Monroe W; Nijnik, Anastasia; Mandl, Judith (Winter)
Winter
15 hours lab/week
Prerequisite: PHGY 419D1
No credit will be given for this course unless both PHGY 419D1 and PHGY 419D2 are successfully completed in consecutive terms
Restriction: Enrolment restricted to U3 Interdepartmental Honours Immunology students or permission of instructors
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PHGY 513 Cellular Immunology (3 credits)
Overview
Physiology : This course deals with cellular interactions, regulation and effector mechanisms of the normal immune response in relation to diseases and pathogenic processes. It is taught at an advanced level.
Terms: Winter 2019
Instructors: Quail, Daniela; Richer, Martin; Divangahi, Maziar; Behr, Marcel A; Rauch, Joyce Ellen; Tsoukas, Christos M; Antel, Jack P; Bernard, Nicole F; Schurr, Erwin; Tremblay, Michel (Winter)
Winter
3 hours lectures plus term paper
Prerequisite: MIMM 314, or permission of the instructor
Complementary Courses (27 credits)
U1 Complementary Courses
6 credits chosen in the following manner.
3 credits selected from:
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BIOL 373 Biometry (3 credits)
Overview
Biology (Sci) : Elementary statistical methods in biology. Introduction to the analysis of biological data with emphasis on the assumptions behind statistical tests and models. Use of statistical techniques typically available on computer packages.
Terms: Fall 2018
Instructors: Leung, Brian (Fall)
Fall
2 hours lecture and 2 hours laboratory
Prerequisite: MATH 112 or equivalent
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.
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MATH 203 Principles of Statistics 1 (3 credits)
Overview
Mathematics & Statistics (Sci) : Examples of statistical data and the use of graphical means to summarize the data. Basic distributions arising in the natural and behavioural sciences. The logical meaning of a test of significance and a confidence interval. Tests of significance and confidence intervals in the one and two sample setting (means, variances and proportions).
Terms: Fall 2018, Winter 2019, Summer 2019
Instructors: Wolfson, David B; Khalili Mahmoudabadi, Abbas (Fall) Wolfson, David B (Winter) Correa, Jose Andres (Summer)
No calculus prerequisites
Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps.
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Students should consult for information regarding transfer credits for this course.
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PSYC 204 Introduction to Psychological Statistics (3 credits)
Overview
Psychology : The statistical analysis of research data; frequency distributions; graphic representation; measures of central tendency and variability; elementary sampling theory and tests of significance.
Terms: Fall 2018, Winter 2019, Summer 2019
Instructors: Amsel, Rhonda N (Fall) Darainy, Mohammad (Winter) Sadikaj, Gentiana (Summer)
Fall and Winter
Restriction: Not open to students who have passed a CEGEP statistics course(s) with a minimum grade of 75%: Mathematics 201-307 or 201-337 or equivalent or the combination of Quantitative Methods 300 with Mathematics 300
This course is a prerequisite for PSYC 305, PSYC 406, PSYC 310, PSYC 336
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.
plus 3 credits selected from the following:
* Students take either PHGY 209 or MIMM 211.
** Students take either CHEM 203 or CHEM 204.
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ANAT 214 Systemic Human Anatomy (3 credits)
Overview
Anatomy & Cell Biology : Introduction to the gross anatomy of the various organ systems of head, neck and trunk regions of the human body. Practical tutorials include studies of prepared specimens, use of the anatomical museum and audio-visual materials. This course is limited in size. Selection of students (other than those requiring the course as part of their program) will be made after the first lecture. (Admission is guaranteed for all students enrolled in programs in the Department of Anatomy and Cell Biology for which ANAT 214 is a required course.)
Terms: Fall 2018
Instructors: Venne, Gabriel (Fall)
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ANAT 262 Introductory Molecular and Cell Biology (3 credits)
Overview
Anatomy & Cell Biology : The architectural, functional and temporal continuity of organelles and the cytoskeleton of mammalian cells is introduced as well as their functional integration in the phenomena of exocytosis, endocytosis, protein trafficking and cell motility and adhesion.
Terms: Winter 2019
Instructors: Presley, John; Stochaj, Ursula; Bechstedt, Susanne; Bui, Khanh Huy (Winter)
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BIOL 202 Basic Genetics (3 credits)
Overview
Biology (Sci) : Introduction to basic principles, and to modern advances, problems and applications in the genetics of higher and lower organisms with examples representative of the biological sciences.
Terms: Winter 2019, Summer 2019
Instructors: Moon, Nam Sung; Nilson, Laura; Western, Tamara (Winter) Dankort, David; Hipfner, David (Summer)
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BIOL 205 Biology of Organisms (3 credits)
Overview
Biology (Sci) : Unified view of form and function in animals and plants. Focus on how the laws of chemistry and physics illuminate biological processes relating to the acquisition of energy and materials and their use in movement, growth, development, reproduction and responses to environmental stress.
Terms: Winter 2019
Instructors: Hargreaves, Anna; Lefebvre, Louis; Hendry, Andrew; Barrett, Rowan; Guigueno, Mélanie; Wilkins, Olivia (Winter)
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BIOL 304 Evolution (3 credits)
Overview
Biology (Sci) : A comprehensive introduction to evolutionary biology. It covers both short-term and long-term evolutionary processes. Topics include the history of life, the origin of species, adaptation, natural selection and sexual selection.
Terms: Fall 2018
Instructors: Bell, Graham (Fall)
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CHEM 203 Survey of Physical Chemistry (3 credits) **
Overview
Chemistry : The fundamentals of thermodynamics and chemical kinetics with applications to biomolecular systems. Thermodynamic and kinetic control of biological processes.
Terms: Fall 2018
Instructors: Kambhampati, Patanjali (Fall)
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CHEM 204 Physical Chemistry/Biological Sciences 1 (3 credits) **
Overview
Chemistry : Similar to CHEM 223/CHEM 243. Emphasis on the use of biological examples to illustrate the principles of physical chemistry. The relevance of physical chemistry to biology is stressed.
Terms: Fall 2018, Winter 2019
Instructors: Cosa, Gonzalo (Fall) Kambhampati, Patanjali (Winter)
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COMP 204 Computer Programming for Life Sciences (3 credits)
Overview
Computer Science (Sci) : Computer Science (Sci): Computer programming in a high level language: variables, expressions, types, functions, conditionals, loops, objects and classes. Introduction to algorithms, modular software design, libraries, file input/output, debugging. Emphasis on applications in the life sciences.
Terms: Fall 2018, Winter 2019
Instructors: Blanchette, Mathieu (Fall) Li, Yue (Winter)
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COMP 250 Introduction to Computer Science (3 credits)
Overview
Computer Science (Sci) : Mathematical tools (binary numbers, induction, recurrence relations, asymptotic complexity, establishing correctness of programs), Data structures (arrays, stacks, queues, linked lists, trees, binary trees, binary search trees, heaps, hash tables), Recursive and non-recursive algorithms (searching and sorting, tree and graph traversal). Abstract data types, inheritance. Selected topics.
Terms: Fall 2018, Winter 2019
Instructors: Langer, Michael; Alberini, Giulia (Fall) Robillard, Martin; Alberini, Giulia (Winter)
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MATH 204 Principles of Statistics 2 (3 credits)
Overview
Mathematics & Statistics (Sci) : The concept of degrees of freedom and the analysis of variability. Planning of experiments. Experimental designs. Polynomial and multiple regressions. Statistical computer packages (no previous computing experience is needed). General statistical procedures requiring few assumptions about the probability model.
Terms: Winter 2019
Instructors: Genest, Christian (Winter)
Winter
Prerequisite: MATH 203 or equivalent. No calculus prerequisites
Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps.
You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.
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MIMM 211 Introductory Microbiology (3 credits) **
Overview
Microbiology and Immun (Sci) : A general treatment of microbiology bearing specifically on the biological properties of microorganisms. Emphasis will be on procaryotic cells. Basic principles of microbial genetics are also introduced.
Terms: Fall 2018
Instructors: Cousineau, Benoit; Nguyen, Dao; Matlashewski, Greg J; Turcotte, Bernard; Gruenheid, Samantha; Archambault, Jacques; Maurice, Corinne (Fall)
Fall
3 hours of lecture
Corequisite: BIOL 200
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MIMM 212 Laboratory in Microbiology (3 credits)
Overview
Microbiology and Immun (Sci) : This laboratory course is designed to complement MIMM 211. Sessions introduce general techniques peculiar to the handling of microorganisms.
Terms: Fall 2018
Instructors: Gruenheid, Samantha (Fall)
Fall
3 hours laboratory, 1 hour lecture, 1 hour follow-up
Corequisite: MIMM 211
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PHGY 209 Mammalian Physiology 1 (3 credits) **
Overview
Physiology : Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.
Terms: Fall 2018
Instructors: Vollrath, Melissa; Gold, Phil; Wechsler, Ann; Ragsdale, David S; Shrier, Alvin; Cook, Erik (Fall)
Fall
3 hours lectures weekly
Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent.
Restriction: Not open to students who have taken PHGY 211 or students who are taking and who have taken NSCI 200.
Restriction: For students in the Faculty of Science, and other students by permission of the instructor
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PHGY 210 Mammalian Physiology 2 (3 credits)
Overview
Physiology : Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.
Terms: Winter 2019
Instructors: Vollrath, Melissa; Campeau, Lysanne; Takano, Tomoko; Guevara, Michael R; Lauzon, Anne-Marie; White, John H (Winter)
Winter
3 hours lectures weekly
Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisite: BIOL 200, BIOL 201, BIOC 212, CHEM 212 or equivalent.
Restriction: For students in the Faculty of Science, and other students by permission of the instructor
Although PHGY 210 may be taken without the prior passing of PHGY 209, students should note that they may have some initial difficulties because of lack of familiarity with some basic concepts introduced in PHGY 209
U2 Complementary Courses
12 credits chosen as follows:
6 credits selected from:
Students may take
* BIOC 220 and BIOC 320, or
** MIMM 384 and MIMM 385, or
*** PHGY 212 and PHGY 213 and BIOL 301
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BIOC 220 Laboratory Methods in Biochemistry and Molecular Biology 1 (3 credits) *
Overview
Biochemistry : Introduction to key methodologies for the isolation, detection and characterization of proteins, lipids, nucleic acids and subcellular fractions, including spectrophotometry, assays of enzymatic activities and chromatographic and electrophoretic methods. Analysis of biochemical data.
Terms: Winter 2019
Instructors: Watson, Ian; Denis, Maxime (Winter)
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BIOC 320 Laboratory Methods in Biochemistry and Molecular Biology 2 (3 credits) *
Overview
Biochemistry : Modern molecular-biological methods for isolation and characterization of nucleic acids and for analysis of RNA and protein expression, including: plasmid expression, isolation, restriction and ligation; electrophoretic methods and Western blotting; PCR and qPCR applications; immunofluorescence microscopy and basic bioinformatics approaches.
Terms: Fall 2018
Instructors: Teodoro, Jose Guerreiro (Fall)
Prerequisite(s): BIOC 220
Restriction(s): Not open to students who have taken BIOC 300D1/D2 or BIOL 301. For students in Biochemistry programs, others with permission of instructor.
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BIOL 301 Cell and Molecular Laboratory (4 credits) ***
Overview
Biology (Sci) : An introduction to laboratory techniques with a focus on methods used to investigate fundamental questions in modern cell and molecular biology. Techniques including gene cloning, DNA and protein isolation and manipulation are covered, along with functional analysis of genes and proteins, basic bioinformatics, and computer-based experimental design and data analysis.
Terms: Fall 2018, Winter 2019
Instructors: Zheng, Huanquan; Harrison, Paul; Reyes Lamothe, Rodrigo (Fall) Zheng, Huanquan; Harrison, Paul; Reyes Lamothe, Rodrigo (Winter)
Fall or Winter
1 hour lecture and one 6-hour laboratory
Prerequisites: PHYS 102 or PHYS 142, BIOL 200, BIOL 201 or ANAT/BIOC 212, and BIOL 202. BIOL 206 recommended.
Restrictions: Not open to students who have taken or are taking BIOC 300. Requires departmental approval.
For approval email anne-marie.sdicu [at] mcgill.ca. Specify your ID number as well as the term and two lab day preferences.
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MIMM 384 Molecular Microbiology Laboratory (3 credits) **
Overview
Microbiology and Immun (Sci) : A series of laboratory exercises in molecular biology and microbial genetics during the Fall term. As part of a term paper writing project, students will explore contemporary research subjects that represent the wide interests of the Microbiology and Immunology departmentâ•Žs faculty. The general objective is to provide practical and theoretical introduction to the technology and methodology used in contemporary microbiology research.
Terms: Fall 2018
Instructors: Cousineau, Benoit; Marczynski, Gregory T; Briedis, Dalius J; Koromilas, Antonis E (Fall)
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MIMM 385 Laboratory in Immunology (3 credits) **
Overview
Microbiology and Immun (Sci) : This laboratory course allows students to gain expertise in following protocols and performing key techniques in immunology. Students also develop basic experimental design and scientific thinking skills by designing their own experiments based on available reagents to solve a problem. Students learn to keep a lab book and communicate scientific findings in written and oral form.
Terms: Winter 2019
Instructors: Fournier, Sylvie; Stegen, Camille (Winter)
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PHGY 212 Introductory Physiology Laboratory 1 (1 credit) ***
Overview
Physiology : Exercises illustrating fundamental principles in physiology: Biological Signals Acquisitions, Blood, Immunology, Neurophysiology, Neuromuscular Physiology.
Terms: Fall 2018
Instructors: Vollrath, Melissa; Glavinovic, Mladen I; Mandl, Judith (Fall)
(One 3-hour lab and one 1-hour lecture every second week.)
Corequisite: PHGY 209.
Restrictions: Required for Physiology students enrolled in PHGY 209. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.
Note: For students in a Physiology program, PHGY 212 should be taken concurrently with PHGY 209.
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PHGY 213 Introductory Physiology Laboratory 2 (1 credit) ***
Overview
Physiology : Exercises illustrating fundamental principles in physiology: Central Nervous System, Cardiovascular, Respiration, Exercise Physiology, Molecular Endocrinology.
Terms: Winter 2019
Instructors: Guevara, Michael R; Mortola, Jacopo; Magder, Sheldon A; White, John H; Vollrath, Melissa (Winter)
(One 3-hour lab and one 1-hour lecture every second week.)
Prerequisite: PHGY 212
Corequisite: PHGY 210.
Restrictions: Required for Physiology students enrolled in PHGY 210. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.
Note: For students in a Physiology program, PHGY 213 should be taken concurrently with PHGY 210.
plus 6 credits, selected from:
* Students take either BIOL 309 or MATH 315, but not both.
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ANAT 365 Cellular Trafficking (3 credits)
Overview
Anatomy & Cell Biology : This course explores the fundamental mechanisms that govern the organizations of intracellular membranes, how vesicle generation is signaled, how the membranes curve and bud, and how vesicles know where to go and fuse. In addition to intracellular vesicles, the principles of mitochondrial dynamics and process of cellular autophagy are examined. Also, there is a focus on "Applied Cell Biology", with respect to how the exquisite regulation of cellular transport plays a central role in complex biological systems. A series of modules will take students through the mechanisms of cellular polarity, neurotransmission, metabolic cell biology, pathogen invasion, and more. The emphasis is on the morphological aspects of the processes, and on the major techniques that led to discovery.
Terms: Fall 2018
Instructors: McBride, Heidi; McPherson, Peter Scott; Kennedy, Timothy E; Stroh, Thomas; Sossin, Wayne Steven; Estall, Jennifer (Fall)
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BIOL 300 Molecular Biology of the Gene (3 credits)
Overview
Biology (Sci) : A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction.
Terms: Fall 2018
Instructors: Schöck, Frieder; Moon, Nam Sung (Fall)
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BIOL 309 Mathematical Models in Biology (3 credits) *
Overview
Biology (Sci) : Application of finite difference and differential equations to problems in cell and developmental biology, ecology and physiology. Qualitative, quantitative and graphical techniques are used to analyze mathematical models and to compare theoretical predictions with experimental data.
Terms: Fall 2018
Instructors: Bub, Gil (Fall)
Fall
3 hours lecture
Prerequisite: one year of calculus. An additional course in calculus is recommended
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BIOL 314 Molecular Biology of Oncogenes (3 credits)
Overview
Biology (Sci) : The genes that cause cancer are altered versions of genes present in normal cells. The origins of these oncogenes, their genetic structure, regulation, and the biochemical properties of the oncogene-encoded proteins will be analyzed in an attempt to understand the origins of human and animal cancers.
Terms: Fall 2018
Instructors: Majewska, Loydie; Christensen, Karen Elizabeth; Del Rincon, Sonia Victoria; Duchaine, Thomas; Dankort, David (Fall)
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CHEM 302 Introductory Organic Chemistry 3 (3 credits)
Overview
Chemistry : Topics covered may include the following: Aromatic compounds, heterocyclic chemistry, sulfur and phosphorus chemistry, organosulfur and organophosphorus compounds, and biomolecules such as lipids, carbohydrates, amino acids, polypeptides, DNA and RNA.
Terms: Fall 2018
Instructors: Damha, Masad J; Gleason, James L (Fall)
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MATH 222 Calculus 3 (3 credits)
Overview
Mathematics & Statistics (Sci) : Taylor series, Taylor's theorem in one and several variables. Review of vector geometry. Partial differentiation, directional derivative. Extreme of functions of 2 or 3 variables. Parametric curves and arc length. Polar and spherical coordinates. Multiple integrals.
Terms: Fall 2018, Winter 2019, Summer 2019
Instructors: Macdonald, Jeremy; Faifman, Dmitry (Fall) Sektnan, Lars (Winter) Pequignot, Yann Batiste (Summer)
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MATH 315 Ordinary Differential Equations (3 credits) *
Overview
Mathematics & Statistics (Sci) : First order ordinary differential equations including elementary numerical methods. Linear differential equations. Laplace transforms. Series solutions.
Terms: Fall 2018, Winter 2019, Summer 2019
Instructors: Nave, Jean-Christophe (Fall) Humphries, Antony Raymond (Winter) Roth, Charles (Summer)
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MIMM 323 Microbial Physiology (3 credits)
Overview
Microbiology and Immun (Sci) : An introduction to the composition and structure of microbial cells, the biochemical activities associated with cellular metabolism and how these activities are regulated and coordinated. The course will have a molecular and genetic approach to the study of microbial physiology.
Terms: Fall 2018
Instructors: Marczynski, Gregory T; Turcotte, Bernard (Fall)
Fall
3 hours of lecture
Prerequisite: MIMM 211
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MIMM 324 Fundamental Virology (3 credits)
Overview
Microbiology and Immun (Sci) : A study of the fundamental properties of viruses and their interactions with host cells. Bacteriophages, DNA- and RNA-containing animal viruses, and retroviruses are covered. Emphasis will be on phenomena occurring at the molecular level and on the regulated control of gene expression in virus-infected cells.
Terms: Fall 2018
Instructors: Sagan, Selena; Teodoro, Jose Guerreiro; Liang, Chen; Briedis, Dalius J; Mouland, Andrew J; Archambault, Jacques (Fall)
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PATH 300 Human Disease (3 credits)
Overview
Pathology : Provides a fundamental understanding of the diseases prevalent in North America, for upper level students in the biological sciences. Includes: general responses of cells and organ systems to injury; assessment of individual diseases by relating the causes, symptoms, diagnosis, treatment and prevention to the primary biological abnormalities in each disorder.
Terms: Winter 2019
Instructors: Zorychta, Edith (Winter)
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PHAR 300 Drug Action (3 credits)
Overview
Pharmacology and Therapeutics : Principles of pharmacology and toxicology. Frequently encountered drugs will be used as a focus to illustrate sites and mechanisms of action, distribution, metabolism, elimination and adverse side effects.
Terms: Fall 2018
Instructors: Zorychta, Edith; Hales, Barbara F (Fall)
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PHAR 301 Drugs and Disease (3 credits)
Overview
Pharmacology and Therapeutics : This course further explores the basic principles of pharmacology as illustrated by drugs used in the treatment of disease. Emphasis is placed on drugs used for diseases prevalent in North America.
Terms: Winter 2019
Instructors: Hales, Barbara F; Clarke, Paul; Bowie, Derek; Castagner, Bastien (Winter)
Winter
Prerequisite: PHAR 300
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PHAR 303 Principles of Toxicology (3 credits)
Overview
Pharmacology and Therapeutics : Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth.
Terms: Winter 2019
Instructors: Robaire, Bernard; Hales, Barbara F; Zorychta, Edith; Baglole, Carolyn; McKeague, Maureen (Winter)
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PHGY 311 Channels, Synapses and Hormones (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system.
Terms: Fall 2018
Instructors: Cooper, Ellis; Sjostrom, Per Jesper; Krishnaswamy, Arjun; Sharif Naeini, Reza (Fall)
Fall
3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term
Prerequisite: PHGY 209 or permission of the instructor.
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PHGY 312 Respiratory, Renal, & Cardiovascular Physiology (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level.
Terms: Winter 2019
Instructors: Hanrahan, John W; Mortola, Jacopo; Shrier, Alvin; Magder, Sheldon A (Winter)
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PHGY 313 Blood, Gastrointestinal, & Immune Systems Physiology (3 credits)
Overview
Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology.
Terms: Winter 2019
Instructors: Mandl, Judith; Mercier, Francois; Orthwein, Alexandre; Kokoeva, Maia; Vollrath, Melissa; Fritz, Jörg; Quail, Daniela (Winter)
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PHGY 314 Integrative Neuroscience (3 credits)
Overview
Physiology : In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours.
Terms: Fall 2018
Instructors: Chacron, Maurice; Sharif Naeini, Reza; Cook, Erik; Pack, Christopher; Shmuel, Amir; Vollrath, Melissa; Brandon, Mark (Fall)
Fall
3 hours of lectures per week
Prerequisites: PHGY 209
U3 Complementary Courses
9 credits of U3 complementary courses chosen in the following manner:
3 credits selected from:
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BIOC 503 Immunochemistry (3 credits)
Overview
Biochemistry : This course, presented in lecture format, emphasizes the molecular, genetic and structure function events that occur in the humoral immune response. Interleukins and other mediators of inflammation, a field in which rapid changes are occurring, are discussed. The clinical significance of fundamental biochemical findings is described.
Terms: Winter 2019
Instructors: Tsoukas, Christos M; Tremblay, Michel (Winter)
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MIMM 509 Inflammatory Processes (3 credits)
Overview
Microbiology and Immun (Sci) : This course concentrates on the non-specific aspects of the immune response, an area which is not adequately covered by the other immunology courses presented at the university. Interactions between guest researchers (from McGill and other universities) and students will be furthered.
Terms: Winter 2019
Instructors: Rauch, Joyce Ellen; Di Battista, Giovanni; Lesage, Sylvie; Richer, Martin; Divangahi, Maziar; Zhang, Ji; King, Irah (Winter)
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PHGY 531 Topics in Applied Immunology (3 credits)
Overview
Physiology : Seminar format course in which experts in immunologic mechanisms of resistance against a variety of infectious diseases, including AIDS, malaria, and tuberculosis oversee student moderators in their presentation of recent scientific literature in the field.
Terms: Winter 2019
Instructors: Stevenson, Mary M; Nguyen, Dao; Ndao, Momar; McCusker, Christine T; Vidal, Silvia; Bernard, Nicole F; Radzioch, Danuta; Fixman, Elizabeth Dee; Qureshi, Salman; Fritz, Jörg (Winter)
plus 6 credits selected from:
* Students take either ANAT 458 or BIOC 458, but not both.
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ANAT 458 Membranes and Cellular Signaling (3 credits) *
Overview
Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
Terms: Winter 2019
Instructors: Denis, Maxime; Autexier, Chantal; Lamarche, Nathalie; Reinhardt, Dieter (Winter)
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BIOC 404 Biophysical Methods in Biochemistry (3 credits)
Overview
Biochemistry : Applications and fundamental bases of important biophysical techniques used in modern biochemistry research laboratories to isolate, characterize and determine the structure and dynamics of proteins, nucleic acids, small molecules and complexes that underlie life and disease.
Terms: Winter 2019
Instructors: Schmeing, Thomas Martin; Trempe, Jean Francois; Denis, Maxime; Hendricks, Adam; Guarne, Alba; Strauss, Michael (Winter)
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BIOC 450 Protein Structure and Function (3 credits)
Overview
Biochemistry : Primary, secondary, tertiary and quaternary structure of enzymes. Active site mapping and site-specific mutagenesis of enzymes. Enzyme kinetics and mechanisms of catalysis. Multienzyme complexes.
Terms: Fall 2018
Instructors: Nagar, Bhushan; Schmeing, Thomas Martin; Purisima, Enrico; Gehring, Kalle Burgess; Berghuis, Albert; von Roretz, Christopher; Young, Jason; Salavati, Reza; Guarne, Alba (Fall)
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BIOC 454 Nucleic Acids (3 credits)
Overview
Biochemistry : RNA processing, localization and stability. RNAi mechanisms, regulation and applications. Regulation of DNA replication. Genomics: human genome sequence, regulation and organization. DNA repair mechanisms. Special topics on transgenics, genetic diseases and cancer.
Terms: Fall 2018
Instructors: Dostie, Josee; Teodoro, Jose Guerreiro; Gallouzi, Imed Eddine; Sonenberg, Nahum; Pelletier, Gerard; Nepveu, Alain; Tremblay, Michel; Bouchard, Maxime; Duchaine, Thomas; Huang, Sidong (Fall)
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BIOC 458 Membranes and Cellular Signaling (3 credits) *
Overview
Biochemistry : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.
Terms: Winter 2019
Instructors: Denis, Maxime; Autexier, Chantal; Lamarche, Nathalie; Reinhardt, Dieter (Winter)
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BIOC 503 Immunochemistry (3 credits)
Overview
Biochemistry : This course, presented in lecture format, emphasizes the molecular, genetic and structure function events that occur in the humoral immune response. Interleukins and other mediators of inflammation, a field in which rapid changes are occurring, are discussed. The clinical significance of fundamental biochemical findings is described.
Terms: Winter 2019
Instructors: Tsoukas, Christos M; Tremblay, Michel (Winter)
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BIOL 520 Gene Activity in Development (3 credits)
Overview
Biology (Sci) : An analysis of the role and regulation of gene expression in several models of eukaryotic development. The emphasis will be on critical evaluation of recent literature concerned with molecular or genetic approaches to the problems of cellular differentiation and determination. Recent research reports will be discussed in conferences and analyzed in written critiques.
Terms: Winter 2019
Instructors: Gerhold, Abigail (Winter)
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EXMD 504 Biology of Cancer (3 credits)
Overview
Experimental Medicine : An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy.
Terms: Fall 2018
Instructors: Topisirovic, Ivan; Fabian, Marc (Fall)
Fall
Prerequisite (Undergraduate): A good knowledge of biology at the cellular and molecular level. Open to U3 and graduate students only
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MIMM 413 Parasitology (3 credits)
Overview
Microbiology and Immun (Sci) : A study of the biology, immunological aspects of host-parasite interactions, pathogenicity, epidemiology and molecular biological aspects of selected parasites of medical importance. Laboratory will consist of a lecture on techniques, demonstrations and practical work.
Terms: Winter 2019
Instructors: Matlashewski, Greg J; Ndao, Momar; Geary, Timothy (Winter)
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MIMM 465 Bacterial Pathogenesis (3 credits)
Overview
Microbiology and Immun (Sci) : Organized by the McGill Centre for the Study of Host Resistance. This course focuses on the interplay of the host and the pathogen. The cellular and molecular basis of the host defense mechanism against infections will be considered in relationship to the virulence factors and evasion strategies used by bacteria to cause disease.
Terms: Fall 2018
Instructors: Reed, Michael; Nguyen, Dao; Behr, Marcel A; Ward, Brian; Gruenheid, Samantha; Veyrier, Frédéric; Maurice, Corinne (Fall)
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MIMM 466 Viral Pathogenesis (3 credits)
Overview
Microbiology and Immun (Sci) : A study of the biological and molecular aspects of viral pathogenesis with emphasis on the human pathogenic viruses including the retroviruses HIV and HTLV-1; herpes viruses; papilloma viruses; hepatitis viruses; and new emerging human viral diseases. These viruses will be discussed in terms of virus multiplication, gene expression virus-induced cytopathic effects and host immune response to infection.
Terms: Winter 2019
Instructors: Liang, Chen; Gatignol, Anne; Briedis, Dalius J; Mouland, Andrew J; Ward, Brian; Routy, Jean-Pierre; Archambault, Jacques; Mesplede, Thibault (Winter)
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MIMM 509 Inflammatory Processes (3 credits)
Overview
Microbiology and Immun (Sci) : This course concentrates on the non-specific aspects of the immune response, an area which is not adequately covered by the other immunology courses presented at the university. Interactions between guest researchers (from McGill and other universities) and students will be furthered.
Terms: Winter 2019
Instructors: Rauch, Joyce Ellen; Di Battista, Giovanni; Lesage, Sylvie; Richer, Martin; Divangahi, Maziar; Zhang, Ji; King, Irah (Winter)
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NEUR 502 Basic and Clinical Aspects of Neuroimmunology (3 credits)
Overview
Neurology and Neurosurgery : The role of inflammation in physiological function of the nervous system, as well as in a broad range of neurological diseases where inflammation can act as a contributing factor to the development of pathology or promote recovery, including fundamentals of neuroimmunology to molecular/cellular aspects of neuroinflammation underlying the pathology seen in clinical conditions.
Terms: Winter 2019
Instructors: Zhang, Ji; Mechawar, Naguib; Luheshi, Giamal; David, Samuel; Antel, Jack P; Hamel, Edith; Stifani, Stefano; Cermakian, Nicolas; Stellwagen, David; King, Irah (Winter)
- PHAR 503 Drug Discovery and Development 1 (3 credits)
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PHAR 504 Drug Discovery and Development 2 (3 credits)
Overview
Pharmacology and Therapeutics : Nobel Prize-winning discoveries as a basis for drug development.
Terms: Winter 2019
Instructors: Maysinger, Dusica; Castagner, Bastien (Winter)
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PHGY 488 Stem Cell Biology (3 credits)
Overview
Physiology : The main concepts in stem cell biology: embryonic stem cells, induced pluripotent stem cells, cancer stem cells, stem cells populations of many adult tissues, applications of stem cell biology and ethical issues surrounding stem cell use in research and medicine. The major experimental methods and laboratory techniques in stem cell biology.
Terms: Fall 2018
Instructors: Nijnik, Anastasia; Ernst, Carl; Gregorieff, Alexander; Eliopoulos, Nicoletta; Stifani, Stefano; Hoesli, Corinne; McCaffrey, Luke; Crist, Colin; Eppert, Kolja (Fall)
Prerequisite(s): PHGY 313 or by permission of instructor.
Restriction(s): Registration is on a first-come, first-served basis.
Restriction(s): Not open to students who are taking or have taken ANAT 416.
Critical reading of peer-reviewed journal papers, practice in oral presentations of scientific material and participation in group discussions.
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PHGY 531 Topics in Applied Immunology (3 credits)
Overview
Physiology : Seminar format course in which experts in immunologic mechanisms of resistance against a variety of infectious diseases, including AIDS, malaria, and tuberculosis oversee student moderators in their presentation of recent scientific literature in the field.
Terms: Winter 2019
Instructors: Stevenson, Mary M; Nguyen, Dao; Ndao, Momar; McCusker, Christine T; Vidal, Silvia; Bernard, Nicole F; Radzioch, Danuta; Fixman, Elizabeth Dee; Qureshi, Salman; Fritz, Jörg (Winter)
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PHGY 552 Cellular and Molecular Physiology (3 credits)
Overview
Physiology : Discussions of recent significant advances in our understanding of the gene products involved in diverse cellular signalling pathways. Topics will include cell-surface hormone receptors, nuclear steroid hormone receptors, and ion channels and transporters. Students will present and critically evaluate experimental approaches, results and interpretations of selected research publications.
Terms: Winter 2019
Instructors: Orlowski, John; White, John H; Stochaj, Ursula; Bernard, Daniel (Winter)
Winter
1 hour lecture, 2 hours seminar weekly
Prerequisite: PHGY 311
Preference will be given to Physiology Honours and Graduate students
Revision, April 2018. End of revision.
Faculty of Science—2018-2019 (last updated Aug. 22, 2018) (disclaimer)
