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Honours Pharmacology (76 credits)

Offered by: Pharmacology and Therapeutics     Degree: Bachelor of Science

Program Requirements

The Honours program is designed as a preparation for graduate studies and research. In addition to the strong training provided by the Major program, it requires students to have direct research experience in a chosen area during their final year of study. Acceptance into the Honours program takes place in the Winter term of U2 and requires a CGPA of 3.50. Students who wish to enter the Honours program should follow the Major program; those who satisfactorily complete the first three terms with a CGPA of at least 3.50 and a mark of B+ or higher in core Pharmacology courses (PHAR 300, PHAR 301, and PHAR 303) are eligible for admission. Applications can be obtained from the office of the Department of Pharmacology in the McIntyre Medical Building or on the Departmental website.

Required Courses (46 credits)

U1

  • BIOL 200 Molecular Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression.

    Terms: Fall 2022

    Instructors: Champetier, Serge; Roy, Richard D W; Hastings, Kenneth E M; Lasko, Paul; Reyes Lamothe, Rodrigo (Fall)

    • Fall

    • 3 hours lecture, 1 hour optional tutorial

    • Prerequisite: BIOL 112 or equivalent

    • Corequisite: CHEM 212 or equivalent, or CHEM 204

  • BIOL 202 Basic Genetics (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Introduction to basic principles, and to modern advances, problems and applications in the genetics of higher and lower organisms with examples representative of the biological sciences.

    Terms: Winter 2023

    Instructors: Moon, Nam Sung; Nilson, Laura; Schoen, Daniel J; Hipfner, David; Champetier, Serge (Winter)

    • Winter

    • 3 hours lecture, 1 hour optional tutorial per week

    • Prerequisite: BIOL 200 or BIOL 219

    • Restriction: Not open to students who have taken or are taking LSCI 204 or BIOL 302.

  • CHEM 212 Introductory Organic Chemistry 1 (4 credits) *

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : A survey of reactions of aliphatic and aromatic compounds including modern concepts of bonding, mechanisms, conformational analysis, and stereochemistry.

    Terms: Fall 2022, Winter 2023, Summer 2023

    Instructors: Pavelka, Laura; Sirjoosingh, Pallavi; Vlaho, Danielle; Gauthier, Jean-Marc (Fall) Vlaho, Danielle; Gauthier, Jean-Marc; Pavelka, Laura; Luedtke, Nathan (Winter) Pavelka, Laura; Vlaho, Danielle; Huot, Mitchell (Summer)

    • Fall, Winter, Summer

    • Prerequisite: CHEM 110 or equivalent.

    • Corequisite: CHEM 120 or equivalent.

    • Restriction: Not open to students who are taking or have taken CHEM 211 or equivalent

    • Each lab section is limited enrolment

    • Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page ().

    • **Due to the intensive nature of this course, the standard add/drop and withdrawal deadlines do not apply. Add/drop is the second lecture day and withdrawal is the fourth lecture day.

  • CHEM 222 Introductory Organic Chemistry 2 (4 credits) *

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Modern spectroscopic techniques for structure determination. The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. Special topics.

    Terms: Fall 2022, Winter 2023, Summer 2023

    Instructors: Vlaho, Danielle; Gauthier, Jean-Marc; Pavelka, Laura; Auclair, Karine (Fall) Pavelka, Laura; Vlaho, Danielle; Gauthier, Jean-Marc (Winter) Pavelka, Laura; Vlaho, Danielle; Huot, Mitchell (Summer)

    • Fall, Winter

    • Prerequisite: CHEM 212 or equivalent.

    • Restriction: Not open to students who have taken an equivalent Organic 2 at CEGEP (see McGill University Basic Math and Sciences Equivalence Table at ) or who have or are taking CHEM 234.

    • **Due to the intensive nature of this course, the standard add/drop and withdrawal deadlines do not apply. Add/drop is the second lecture day and withdrawal is the fourth lecture day.

  • PHAR 200 Introduction to Pharmacology 1 (1 credit)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : The objective of this course is to give U1 Pharmacology Major program students an appreciation of research in Pharmacology. The focus will be on contributions of this research to our understanding of how drugs work, strategies towards the discovery of new drugs, and/or on how use of current drugs may be improved based on this understanding.

    Terms: Fall 2022

    Instructors: Hales, Barbara F; Trempe, Jean-Francois; Robaire, Bernard; Garofalo, Lorella; Clarke, Paul; Bowie, Derek; McKinney, R. Anne; Rousseau, Simon; Tanny, Jason; Munter, Lisa (Fall)

    • Restriction(s): Only open to students in the BSc. Major in Pharmacology.

  • PHAR 201 Introduction to Pharmacology 2 (1 credit)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This course will be a continuation of PHAR 200, taught in the fall semester. The focus will be on contributions of this research to our understanding of how drugs work, strategies towards the discovery of new drugs, and/or on how use of current drugs may be improved based on this understanding.

    Terms: Winter 2023

    Instructors: Hales, Barbara F; Basik, Mark; Mann, Koren; Trasler, Jacquetta M; Szyf, Moshe; Thanabalasuriar, Ajitha; Hebert, Terence; McKinney, R. Anne; Kimmins, Sarah; Bernard, Daniel (Winter)

    • Prerequisite(s): PHAR 200

    • Restriction(s): Only open to students in the BSc. Major in Pharmacology.

  • PHGY 209 Mammalian Physiology 1 (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.

    Terms: Fall 2022

    Instructors: Vollrath, Melissa; Grisaru Wechsler, Ann; Ragsdale, David S; Shrier, Alvin; Cook, Erik; Aguer, Céline (Fall)

  • PHGY 210 Mammalian Physiology 2 (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.

    Terms: Winter 2023

    Instructors: Vollrath, Melissa; Takano, Tomoko; Guevara, Michael R; Lauzon, Anne-Marie; White, John H; Aguer, Céline (Winter)

  • PHGY 212 Introductory Physiology Laboratory 1 (1 credit)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Exercises illustrating fundamental principles in physiology: Biological Signals Acquisitions, Blood, Immunology, Neurophysiology, Neuromuscular Physiology.

    Terms: Fall 2022

    Instructors: Vollrath, Melissa; Glavinovic, Mladen I; Mandl, Judith (Fall)

    • (One 3-hour lab and one 1-hour lecture every second week.)

    • Corequisite: PHGY 209.

    • Restrictions: Required for Physiology students enrolled in PHGY 209. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.

    • Note: For students in a Physiology program, PHGY 212 should be taken concurrently with PHGY 209.

  • PHGY 213 Introductory Physiology Laboratory 2 (1 credit)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Exercises illustrating fundamental principles in physiology: Central Nervous System, Cardiovascular, Respiration, Exercise Physiology, Molecular Endocrinology.

    Terms: Winter 2023

    Instructors: Guevara, Michael R; Magder, Sheldon A; White, John H; Vollrath, Melissa; Smith, Benjamin (Winter)

    • (One 3-hour lab and one 1-hour lecture every second week.)

    • Prerequisite: PHGY 212

    • Corequisite: PHGY 210.

    • Restrictions: Required for Physiology students enrolled in PHGY 210. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.

    • Note: For students in a Physiology program, PHGY 213 should be taken concurrently with PHGY 210.

U2

  • BIOC 311 Metabolic Biochemistry (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : The generation of metabolic energy in higher organisms with an emphasis on its regulation at the molecular, cellular and organ level. Chemical concepts and mechanisms of enzymatic catalysis are also emphasized. Included: selected topics in carbohydrate, lipid and nitrogen metabolism; complex lipids and biological membranes; hormonal signal transduction.

    Terms: Fall 2022

    Instructors: Denis, Maxime; Giguere, Vincent; Gehring, Kalle; Kazak, Lawrence (Fall)

  • BIOL 301 Cell and Molecular Laboratory (4 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : An introduction to biology research and communication with a focus on cell and molecular biology. Through conducting a series of project-based experiments and writing a final report, molecular and synthetic biology techniques such as gene cloning, manipulation, protein isolation and characterization and how research is conducted, analyzed and communicated will be addressed. In addition, an introduction to bioinformatics methods and their role in analysis will be provided.

    Terms: Fall 2022, Winter 2023

    Instructors: Reyes Lamothe, Rodrigo; Harrison, Paul; Leroux, Maxime (Fall) Hayer, Arnold; Harrison, Paul; Leroux, Maxime (Winter)

    • Fall or Winter

    • 1 hour lecture and one 6-hour laboratory

    • Prerequisites: BIOL 200, BIOL 201 (or ANAT 212/BIOC 212); or BIOL 219

    • Restrictions: Not open to students who have taken or are taking BIOC 300, or BIOC 220 and BIOC 320. Requires departmental approval.

    • For approval email hugo.zheng [at] mcgill.ca. Specify your ID number as well as the term and two lab day preferences.

  • PHAR 300 Drug Action (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Principles of pharmacology and toxicology. Frequently encountered drugs will be used as a focus to illustrate sites and mechanisms of action, distribution, metabolism, elimination and adverse side effects.

    Terms: Fall 2022

    Instructors: Zorychta, Edith; Hales, Barbara F; Thanabalasuriar, Ajitha (Fall)

  • PHAR 301 Drugs and Disease (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This course further explores the basic principles of pharmacology as illustrated by drugs used in the treatment of disease. Emphasis is placed on drugs used for diseases prevalent in North America.

    Terms: Winter 2023

    Instructors: Castagner, Bastien; Hales, Barbara F; Clarke, Paul; Bowie, Derek; Thanabalasuriar, Ajitha (Winter)

  • PHAR 303 Principles of Toxicology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth.

    Terms: Winter 2023

    Instructors: McKeague, Maureen; Hales, Barbara F; Zorychta, Edith; Robaire, Bernard; Baglole, Carolyn (Winter)

U3

  • PHAR 598D1 Honours Pharmacology Research Project (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Supervised Honours Research Project in Pharmacology. Students are expected to obtain hands-on research experience in their supervisor's laboratory. They are also required to submit a written report in the form of a scientific manuscript and present a ten minute seminar.

    Terms: Fall 2022, Winter 2023

    Instructors: Maysinger, Dusica; Szyf, Moshe; McKinney, R. Anne (Fall) McKinney, R. Anne; Maysinger, Dusica; Szyf, Moshe (Winter)

    • Corequisite(s): PHAR 562 General Pharmacology 1

    • Corequisite(s): PHAR 563 General Pharmacology 2

    • Restriction(s): Only open to U3 students accepted in the BSc. Honours Pharmacology. Requires Departmental approval.

    • Students must register for both PHAR 598 D1 and PHAR 598 D2.

    • No credit will be given for this course unless both PHAR 598 D1 and PHAR 598 D2 are successfully completed in consecutive terms.

    • Minimum of 9 hours/week to be spent in the lab.

    • A statement of the proposed project and method of evaluation, signed by the student and supervisor, must be submitted to the departmental Director of Undergraduate Studies for approval by the add/drop deadline of the semester in which the student registers for this course.

  • PHAR 598D2 Honours Pharmacology Research Project (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : See PHAR 598D1 for course description.

    Terms: Fall 2022, Winter 2023, Summer 2023

    Instructors: Maysinger, Dusica; Szyf, Moshe; McKinney, R. Anne (Fall) Maysinger, Dusica; Szyf, Moshe; McKinney, R. Anne (Winter) McKinney, R. Anne; Maysinger, Dusica; Szyf, Moshe (Summer)

    • Prerequisite(s): PHAR 598D1

    • Students must register for both PHAR 598 D1 and PHAR 598 D2.

    • No credit will be given for this course unless both PHAR 598 D1 and PHAR 598 D2 are successfully completed in consecutive terms.

* Students who have taken the equivalent of CHEM 212, CHEM 222, and/or MATH 203 in CEGEP (as defined at : ) are exempt and may not take these courses at McGill. Students must replace these credits with appropriate complementary cours4e credits to satisfy the total credit requirement for their degree.

Complementary Courses (30 credits)

3 credits selected from the following (highly recommended in Year 1):

  • ANAT 212 Molecular Mechanisms of Cell Function (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.

    Terms: Winter 2023

    Instructors: Vera Ugalde, Maria; Reinhardt, Dieter; Fabian, Marc; Kiss, Robert; Pastor, William (Winter)

  • BIOC 212 Molecular Mechanisms of Cell Function (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.

    Terms: Winter 2023

    Instructors: Pause, Arnim; Reinhardt, Dieter; Duchaine, Thomas; Kiss, Robert; Vera Ugalde, Maria (Winter)

    • Winter

    • Prerequisite: BIOL 200

    • Restrictions: A non-terminal course intended to be followed by BIOC 311; BIOC 312 in the U2 year. Not open to students who have taken or are taking BIOL 201 or ANAT 212.

  • BIOL 201 Cell Biology and Metabolism (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : This course introduces the student to our modern understanding of cells and how they work. Major topics to be covered include: photosynthesis, energy metabolism and metabolic integration; plasma membrane including secretion, endocytosis and contact mediated interactions between cells; cytoskeleton including cell and organelle movement; the nervous system; hormone signaling; the cell cycle.

    Terms: Winter 2023

    Instructors: Brouhard, Gary; Champetier, Serge (Winter)

    • Winter

    • 3 hours lecture, 1 hour optional tutorial

    • Prerequisite: BIOL 200.

    • Restriction: Not open to students who have taken or are taking ANAT 212 or BIOC 212

3 credits selected from the following (usually in Year 2):

  • CHEM 203 Survey of Physical Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : The fundamentals of thermodynamics and chemical kinetics with applications to biomolecular systems. Thermodynamic and kinetic control of biological processes.

    Terms: Fall 2022

    Instructors: Kambhampati, Patanjali (Fall)

    • Fall

    • Prerequisites: CHEM 110 and CHEM 120 or equivalent.

    • Restrictions: Intended for students in biological science programs requiring only one course in physical chemistry. Not open to students who have taken or are taking CHEM 204 or CHEM 213 or CHEM 223 and CHEM 243.

  • CHEM 204 Physical Chemistry/Biological Sciences 1 (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Similar to CHEM 223/CHEM 243. Emphasis on the use of biological examples to illustrate the principles of physical chemistry. The relevance of physical chemistry to biology is stressed.

    Terms: Fall 2022, Winter 2023

    Instructors: Simine, Yelena (Fall) Khaliullin, Rustam (Winter)

    • Fall, Winter

    • Prerequisites: CHEM 110 and CHEM 120 or equivalent and one full course in calculus

    • Restriction: Not open to students who have taken or are taking CHEM 203 or CHEM 213.

3 credits selected from the following (usually in Year 2):

  • BIOL 373 Biometry (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Elementary statistical methods in biology. Introduction to the analysis of biological data with emphasis on the assumptions behind statistical tests and models. Use of statistical techniques typically available on computer packages.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

    • Fall

    • 2 hours lecture and 2 hours laboratory

    • Prerequisite: MATH 112 or equivalent

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.

  • MATH 203 Principles of Statistics 1 (3 credits) *

    Offered by: Mathematics and Statistics (Faculty of Science)

    Overview

    Mathematics & Statistics (Sci) : Examples of statistical data and the use of graphical means to summarize the data. Basic distributions arising in the natural and behavioural sciences. The logical meaning of a test of significance and a confidence interval. Tests of significance and confidence intervals in the one and two sample setting (means, variances and proportions).

    Terms: Fall 2022, Winter 2023, Summer 2023

    Instructors: Sajjad, Alia; Kreitewolf, Jens (Fall) Nadarajah, Tharshanna (Winter) Sajjad, Alia (Summer)

    • No calculus prerequisites

    • Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps.

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Students should consult for information regarding transfer credits for this course.

  • PSYC 204 Introduction to Psychological Statistics (3 credits)

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : The statistical analysis of research data; frequency distributions; graphic representation; measures of central tendency and variability; elementary sampling theory and tests of significance.

    Terms: Fall 2022, Winter 2023, Summer 2023

    Instructors: Flake, Jessica (Fall) Kreitewolf, Jens (Winter) Kreitewolf, Jens (Summer)

    • Fall and Winter

    • Restriction: Not open to students who have passed a CEGEP statistics course(s) with a minimum grade of 75%: Mathematics 201-307 or 201-337 or equivalent or the combination of Quantitative Methods 300 with Mathematics 300

    • This course is a prerequisite for PSYC 305, PSYC 406, PSYC 310, PSYC 336

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.

12 credits selected from the following Pharmacology courses:

  • PHAR 390 Laboratory in Pharmacology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This course is a two-week all day practical laboratory course where students will have the opportunity to design their own experiments, write out the experimental lab reports and learn to trouble shoot on their own.

    Terms: Summer 2023

    Instructors: Munter, Lisa (Summer)

    • Restriction(s): Restricted to Pharmacology Honours students, or permission of instructor.

  • PHAR 503 Drug Discovery and Development 1 (3 credits) **

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Chemistry, mechanisms of action, and steps in drug discovery and development.

    Terms: Fall 2022

    Instructors: Munter, Lisa; Sharif Naeini, Reza; Meerovitch, Karen; Mooser, Vincent (Fall)

  • PHAR 504 Drug Discovery and Development 2 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Nobel Prize-winning discoveries as a basis for drug development.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

    • Winter

    • Prerequisites: PHAR 301 or PHAR 303; or permission of instructor

    • Restriction: U3 and graduate students. Students can register only with permission of coordinators.

  • PHAR 505 Structural Pharmacology (3 credits) **

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : The course will cover approaches widely used in the pharmaceuticals industry, such as drug target selection, structure determination and medicinal chemistry. The basics of structural biology will be taught in a very visual and interactive manner, with an emphasis on drug:target interactions and chemical principles relevant to drug design. By the end of the course, the students will become familiar with the structure-based drug discovery process and principles of molecular pharmacology.

    Terms: Fall 2022

    Instructors: Trempe, Jean-Francois; Corbeil, Christopher; Castagner, Bastien (Fall)

    • Prerequisite(s): PHAR 301, BIOC 311 or with permission of instructor

    • Restriction(s): Not open to students who have taken or are taking PHAR 503.

  • PHAR 508 Drug Discovery and Development 3 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : The design of biologically-relevant drug screens for molecular targets in a cell, tissue, and in vivo setting. Explore the use of stem cells and tissue-based disease models for the understanding of disease and for drug discovery. Situate modern pharmacology into broader medical and societal issues such as personalized medicine and the ethics associated with research.

    Terms: Winter 2023

    Instructors: Hebert, Terence; Clarke, Paul; Tanny, Jason (Winter)

    • Prerequisite(s): PHAR 301 (PHAR 503 or PHAR 505 are also highly recommended)

    • Restriction(s): Open to U3 students in the minor, major or honours program in Pharmacology.

    • Not open to students who have taken PHAR 558.

    • Assessment modalities- in class presentations and discussion, take-home exams and writing exercises.

  • PHAR 510 New Advances in Antimicrobial (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Overview on bacteria, insights into bacterial pathogenesis, an understanding of antibiotics, and new developments in antibacterial to beat antibiotic resistance.

    Terms: Winter 2023

    Instructors: Thanabalasuriar, Ajitha; Castagner, Bastien; Cuella Martin, Raquel (Winter)

    • Restrictions: Open to U3 students and above. Class capacity is first come first serve, after the first 15 students, the next 10 students priority will be given to MIMM and PHAR students. Not open to students who have taken or are taking MIMM 510.

  • PHAR 540 Advances in Industrial Biotechnology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Introduction to emerging technologies and research advances in biotechnologies. Topics include semisynthetic production of drugs and drug candidates through large-scale fermentation, next generation synthesis of DNA and whole genes, green toxicology, single-molecule diagnostics, orphan-drug re-purposing, and next- generation genomic analyses in drug development. Translational research, issues of entrepreneurship, sustainability, and ethics are also covered.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

    • Prerequisite: CHEM 222 (or equivalent) and BIOL 200 or CHEM 332

    • Restriction: U3 Students or higher. Not open to students who have taken or are taking CHEM 540.

  • PHAR 562 Neuropharmacology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Topics in pharmacology with an emphasis on molecular mechanisms of drug-action and cellular targets in the nervous system.

    Terms: Fall 2022

    Instructors: Bowie, Derek; Trempe, Jean-Francois; Leyton, Marco; McKinney, R. Anne; Stellwagen, David; Khoutorsky, Arkady; Multhaup, Gerhard; Munter, Lisa (Fall)

    • Fall

    • Prerequisite: PHAR 301 or with permission of instructor.

    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.

  • PHAR 563 Endocrine Pharmacology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This advanced course covers selected topics in pharmacology of reproductive, endocrine, and metabolic disorders.

    Terms: Fall 2022

    Instructors: Bernard, Daniel; Robaire, Bernard; Trasler, Jacquetta M (Fall)

    • Prerequisite: PHAR 301 or permission of the instructor(s)

    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.

    • Course material will be presented in the form of lectures and student-led presentations.

  • PHAR 565 Epigenetic Drugs and Targets (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This course covers therapeutics targeting epigenetic mechanisms. Although only a handful of epigenetic drugs are in widespread use, further development of such agents is a very active area of research as it has the potential to directly target aberrant gene expression. This course will examine both the current use and potential of epigenetic drugs in treatment of cancer, neurological diseases, immune disorders, and cardiovascular disease. The concept of epigenetics as mediating gene-environment interaction will also be discussed.

    Terms: Winter 2023

    Instructors: Tanny, Jason; Trasler, Jacquetta M; Szyf, Moshe (Winter)

    • Prerequisite(s): PHAR 301.

    • Restrictions: Not open to students who have taken or are taking HGEN 673.

9 credits selected for the following science courses:

Committee approval is required to substitute a science course not in the list below.

  • ANAT 321 Circuitry of the Human Brain (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course explores the functional organization of the human brain and spinal cord. The course focuses on how neuronal systems are designed to subserve specific motor, sensory, and cognitive operations.

    Terms: Fall 2022

    Instructors: Ragsdale, David S (Fall)

  • ANAT 322 Neuroendocrinology (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : A lecture course describing brain-endocrine relationships. Emphasis on modern experimental evidence and conceptual developments within the field.

    Terms: Winter 2023

    Instructors: Walker, Claire; Stroh, Thomas; Tamilia, Michael; Cermakian, Nicolas; Bernard, Daniel; Kokoeva, Maia; Storch, Kai-Florian; Sabatini, Paul (Winter)

    • Winter

    • 3 hours lecture

    • Prerequisite: PHGY 210.

  • ANAT 365 Cellular Trafficking (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course explores the fundamental mechanisms that govern the organizations of intracellular membranes, how vesicle generation is signaled, how the membranes curve and bud, and how vesicles know where to go and fuse. In addition to intracellular vesicles, the principles of mitochondrial dynamics and process of cellular autophagy are examined. Also, there is a focus on "Applied Cell Biology", with respect to how the exquisite regulation of cellular transport plays a central role in complex biological systems. A series of modules will take students through the mechanisms of cellular polarity, neurotransmission, metabolic cell biology, pathogen invasion, and more. The emphasis is on the morphological aspects of the processes, and on the major techniques that led to discovery.

    Terms: Fall 2022

    Instructors: McBride, Heidi; Kennedy, Timothy E; Stroh, Thomas; Sossin, Wayne Steven; Estall, Jennifer; Zeytuni, Natalie (Fall)

  • ANAT 381 Experimental Embryology (3 credits) +

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : The basic processes of reproduction and embryonic development, such as molecular signaling; cell-cell interaction; differentiation; cell fate determination; genetic and epigenetic control of embryonic development.

    Terms: Fall 2022

    Instructors: Nagano, Makoto; Ao, Asangla; Ryan, Aimee; Clarke, Hugh; Tanny, Jason (Fall)

    • Fall

    • 3 hour lectures

    • Prerequisites: ANAT 261, BIOL 202 or permission of instructor

    • Restriction(s): Not open to students who have taken BIOL 303.

  • ANAT 458 Membranes and Cellular Signaling (3 credits) *

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.

    Terms: Winter 2023

    Instructors: Denis, Maxime; Autexier, Chantal; Lamarche, Nathalie; Reinhardt, Dieter (Winter)

  • BIEN 510 Engineered Nanomaterials for Biomedical Applications (3 credits)

    Offered by: Bioengineering (Faculty of Engineering)

    Overview

    BIEN : Introduction to the interdisciplinary field of biomedical uses of nanotechnology. Emphasis on emerging nanotechnologies and biomedical applications including nanomaterials, nanoengineering, nanotechnology-based drug delivery systems, nano-based imaging and diagnostic systems, nanotoxicology and immunology, and translating nanomedicine into clinical investigation.

    Terms: Fall 2022

    Instructors: Kinsella, Matt (Fall)

  • BIOC 312 Biochemistry of Macromolecules (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Gene expression from the start of transcription to the synthesis of proteins, their modifications and degradation. Topics covered: purine and pyrimidine metabolism; transcription and its regulation; mRNA processing; translation; targeting of proteins to specific cellular sites; protein glycosylation; protein phosphorylation; protein turn-over; programmed cell death (apoptosis).

    Terms: Winter 2023

    Instructors: Huang, Sidong; Richard, Stephane; Sonenberg, Nahum; Pelletier, Gerard; Tremblay, Michel; Dostie, Josee; Giguere, Vincent (Winter)

  • BIOC 450 Protein Structure and Function (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Primary, secondary, tertiary and quaternary structure of enzymes. Active site mapping and site-specific mutagenesis of enzymes. Enzyme kinetics and mechanisms of catalysis. Multienzyme complexes.

    Terms: Fall 2022

    Instructors: Nagar, Bhushan; Schmeing, Thomas Martin; Purisima, Enrico; Gehring, Kalle; Berghuis, Albert; von Roretz, Christopher; Salavati, Reza; Guarne, Alba (Fall)

    • Fall

    • Prerequisites: BIOC 311, BIOC 312 and/or sufficient organic chemistry.

    • Restriction: Intended primarily for students at the U3 level

  • BIOC 454 Nucleic Acids (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : RNA processing, localization and stability. RNAi mechanisms, regulation and applications. Regulation of DNA replication. Genomics: human genome sequence, regulation and organization. DNA repair mechanisms. Special topics on transgenics, genetic diseases and cancer.

    Terms: Fall 2022

    Instructors: Pastor, William; Teodoro, Jose Guerreiro; Gallouzi, Imed Eddine; Nepveu, Alain; Dostie, Josee; Duchaine, Thomas; Huang, Sidong; Watson, Ian (Fall)

  • BIOC 458 Membranes and Cellular Signaling (3 credits) *

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.

    Terms: Winter 2023

    Instructors: Denis, Maxime; Autexier, Chantal; Lamarche, Nathalie; Reinhardt, Dieter (Winter)

  • BIOC 470 Lipids and Lipoproteins in Disease (3 credits) ***

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Structure, function and metabolism of lipids and lipoproteins as they relate to lipid storage diseases, obesity, insulin resistance, diabetes, heart disease, Alzheimers disease and other neurological diseases. Transcriptional and post-translational mechanisms governing the synthesis and degradation of important enzymes, lipids, and lipid transport molecules; role of lipid mediators in signaling pathways and protein modification; assembly and dynamics of lipoproteins and biological membranes; genetic disruptions of lipid regulatory proteins such as cell surface receptors leading to human disease.

    Terms: Winter 2023

    Instructors: Kiss, Robert; Nilsson, Tommy (Winter)

    • Prerequisite(s): BIOC 311 or equivalent.

  • BIOL 300 Molecular Biology of the Gene (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction.

    Terms: Fall 2022

    Instructors: Schöck, Frieder; Moon, Nam Sung (Fall)

  • BIOL 303 Developmental Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A consideration of the fundamental processes and principles operating during embryogenesis. Experimental analyses at the molecular, cellular, and organismal levels will be presented and discussed to provide an overall appreciation of developmental phenomena.

    Terms: Winter 2023

    Instructors: Gerhold, Abigail; Rao, Yong; Dufort, Daniel (Winter)

  • BIOL 306 Neural Basis of Behaviour (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Neural mechanisms of animal behaviour; neuroethology; cellular neurophysiology, integrative networks within nervous systems; neural control of movement; processing of sensory information.

    Terms: Fall 2022

    Instructors: Sakata, Jon; Dent, Joseph Alan (Fall)

  • BIOL 314 Molecular Biology of Cancer (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : The molecular basis of human cancers, including analyzing the events that promote the formation of oncogenes and inhibit tumour suppressor genes, the biochemical properties of the proteins encoded by these genes, and their functions. Current molecular targets for cancer therapy and the concepts and consequences of inheriting mutations in genes that predispose to cancer.

    Terms: Winter 2023

    Instructors: Dankort, David (Winter)

  • BIOL 370 Human Genetics Applied (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A contemporary view of genetic research as applied to human health and well-being.

    Terms: Fall 2022

    Instructors: Palmour, Roberta M; Richards, John Brent; Trakadis, Yannis; Ernst, Carl; Ao, Asangla; Fitzpatrick, Jennifer; Engert, Jamie; Bailey, Swneke; Majewska, Loydie; Kitzler, Thomas (Fall)

  • BIOT 505 Selected Topics in Biotechnology (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Biotechnology : Current methods and recent advances in biological, medical, agricultural and engineering aspects of biotechnology will be described and discussed. An extensive reading list will complement the lecture material.

    Terms: Fall 2022

    Instructors: Moores, Audrey; Luedtke, Nathan (Fall)

    • Fall

    • Restriction: U3 students

  • CHEM 302 Introductory Organic Chemistry 3 (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Topics covered may include the following: Aromatic compounds, heterocyclic chemistry, sulfur and phosphorus chemistry, organosulfur and organophosphorus compounds, and biomolecules such as lipids, carbohydrates, amino acids, polypeptides, DNA and RNA.

    Terms: Fall 2022

    Instructors: Damha, Masad J (Fall)

    • Fall, Winter

    • Prerequisites: CHEM 222, or permission of the instructor.

  • CHEM 334 Advanced Materials (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Survey of the physical and chemical structure-function relationships defining advanced materials, including an introduction to basic materials science and characterization. Topics include supramolecular polymers, self-healing materials, advanced surfaces and adhesives, bio-inspired materials, shape memory materials, sensors and actuators, and photonic materials.

    Terms: Winter 2023

    Instructors: Harrington, Matthew (Winter)

  • CHEM 462 Green Chemistry (3 credits) +

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : New reactions and methods which can be used for the production of chemicals from renewable feedstocks; the use of new environmentally benign solvents, catalysts and reagents; organic reactions in aqueous media and in supercritical carbon dioxide; bio-catalysis and bio-processes.

    Terms: Winter 2023

    Instructors: Li, Chaojun (Winter)

  • CHEM 502 Advanced Bio-Organic Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : This course will cover biologically relevant molecules, particularly nucleic acids, proteins, and their building blocks. In each case, synthesis and biological functions will be discussed. The topics include synthesis of oligonucleotides and peptides; chemistry of phosphates; enzyme structure and function; coenzymes, and enzyme catalysis; polyketides; antiviral and anticancer agents.

    Terms: Winter 2023

    Instructors: Thibodeaux, Christopher; Luedtke, Nathan (Winter)

    • Winter

    • Prerequisite: CHEM 302

    • Restriction: Not open to students who have taken CHEM 402.

  • CHEM 503 Drug Discovery (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : The aim of this course is to provide an introduction to the overall drug discovery process. The main focus of the course will be on medicinal chemistry, synthesis and catalysis, as they relate to large-scale production of pharmaceutical agents. However, other aspects of drug discovery, including structural research (e.g. NMR, X-ray), biochemistry, drug metabolism and bioavailability will also be included.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

  • CHEM 522 Stereochemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Stereoisomers, their nomenclature and configuration. Conformational analysis, separation of stereoisomers, and stereocontrol in organic synthesis.

    Terms: Fall 2022

    Instructors: Moitessier, Nicolas (Fall)

    • Winter

    • Prerequisite: CHEM 302

    • Restriction: Not open to students who have taken CHEM 623

  • CHEM 552 Physical Organic Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : The correlation of theory with physical measurements on organic systems; an introduction to photochemistry; solvent and substituent effects on organic reaction rates, etc.; reaction mechanisms.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

  • COMP 204 Computer Programming for Life Sciences (3 credits)

    Offered by: Computer Science (Faculty of Science)

    Overview

    Computer Science (Sci) : Computer Science (Sci): Computer programming in a high level language: variables, expressions, types, functions, conditionals, loops, objects and classes. Introduction to algorithms, modular software design, libraries, file input/output, debugging. Emphasis on applications in the life sciences.

    Terms: Fall 2022, Winter 2023

    Instructors: Becerra, David (Fall) Becerra, David (Winter)

    • Prerequisite(s): CEGEP level mathematics course.

    • Co-requisite: BIOL 112

    • Restrictions: Not open to students who have taken or are taking COMP 202, COMP 208, or GEOG 333; not open to students who have taken or are taking COMP 206 or COMP 250.

  • EXMD 401 Physiology and Biochemistry Endocrine Systems (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Offered in conjunction with the Department of Physiology. The course provides a basic knowledge of endocrine systems encompassing biosynthesis, metabolism and physiological actions of hormones. Specific topics covered are hormones of the hypothalamus, pituitary, adrenals, thyroids, parathyroids, pancreas, gut and the gonads. The role of hormones and growth factors in pregnancy and fetal development are also discussed.

    Terms: Winter 2023

    Instructors: Liu, Jun-Li; Bateman, Andrew; O'Flaherty, Cristian; Bernard, Daniel; Murshed, Monzur; Sabatini, Paul (Winter)

  • EXMD 504 Biology of Cancer (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy.

    Terms: Fall 2022

    Instructors: Garzia, Livia; Teodoro, Jose Guerreiro; Gold, Phil; Brodt, Penina; Tonin, Patricia; Bailey, Swneke; Duchaine, Thomas; Malagón, Talía; Jung, Sungmi; Labbé, David (Fall)

    • Fall

    • Prerequisite (Undergraduate): A good knowledge of biology at the cellular and molecular level. Open to U3 and graduate students only

  • EXMD 509 Gastrointestinal Physiology and Pathology (3 credits) ***

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Course deals with various aspects of gastrointestinal and hepatic function in health and altered physiological states. The principal focus is on the recent literature pertaining to cell and molecular mechanisms underlying the motility secretory process, absorption and secretion. The molecular biology of the hepatic viruses and various aspects of colonic neoplasia will also be considered.

    Terms: Fall 2022, Winter 2023

    Instructors: Wild, Gary Edward (Fall) Wild, Gary Edward (Winter)

    • Fall and Winter

    • Prerequisite: Graduate students, U3 undergraduates

  • EXMD 511 Joint Venturing with Industry (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Using problem-based learning, the course examines the various business interactions between researchers and their business partners in support and development of research into commercial endeavours using models such as venture capital, business partnerships, or grants-in-aid.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

    • Winter

    • Offered in conjunction with the Centre for Continuing Education

  • HGEN 400 Genetics in Medicine (3 credits) ***

    Offered by: Human Genetics (Faculty of Science)

    Overview

    Human Genetics : Using clinical vignettes, this course will emphasize the principles, ethical and legal issues of human heredity in medical genetics in the context of nature and genetic diversity of the human population.

    Terms: Winter 2023

    Instructors: Ragoussis, Ioannis; Fitzpatrick, Jennifer; Foulkes, William; Sladek, Robert; Campeau, Philippe; Joly, Yann; Lavoie, Josee; Braverman, Nancy; Riaz Alhosseini, Yasser; Dalpe, Gratien (Winter)

  • MIMM 387 The Business of Science (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : The ability to select and manipulate genetic material has led to unprecedented interest in the industrial applications of procaryotic and eucaryotic cells. Beginning in the 1970s the introduction of and subsequent refinements to recombinant DNA technology and hybridoma technology transformed the horizons of the biopharmaceutical world. This course will highlight the important events that link basic research to clinical/commercial application of new drugs and chemicals.

    Terms: Winter 2023

    Instructors: Kukolj, George; Antel, Jack P; Ward, Brian; Gruenheid, Samantha (Winter)

    • Winter

    • Prerequisite: At least one 200-level course in a biological or biomedical discipline or permission of instructor

  • MIMM 414 Advanced Immunology (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : An advanced course serving as a logical extension of MIMM 314. The course will integrate molecular, cellular and biochemical events involved in the ontogeny of the lymphoid system and its activation in the immune response. The course will provide the student with an up-to-date understanding of a rapidly moving field.

    Terms: Fall 2022

    Instructors: Fritz, Jörg (Fall)

    • Fall

    • 3 hour lecture

    • Prerequisite: MIMM 314

  • MIMM 466 Viral Pathogenesis (3 credits) ++

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : A study of the biological and molecular aspects of viral pathogenesis with emphasis on the human pathogenic viruses including the retroviruses HIV and HTLV-1; herpes viruses; papilloma viruses; hepatitis viruses; and new emerging human viral diseases. These viruses will be discussed in terms of virus multiplication, gene expression virus-induced cytopathic effects and host immune response to infection.

    Terms: Winter 2023

    Instructors: Liang, Chen; Gatignol, Anne; Briedis, Dalius J; Mouland, Andrew J; Routy, Jean-Pierre; Daniels, Sylvanne (Winter)

  • NEUR 310 Cellular Neurobiology (3 credits)

    Offered by: Neurology and Neurosurgery (Faculty of Science)

    Overview

    Neurology and Neurosurgery : A survey of the functional organization of nerve cells, signalling in the nervous system, and principles of neural development. Topics include cell polarity, neurotransmitters, neurotrophins, receptors and second messengers, cell lineage, guidance of axon outgrowth, and nerve regeneration. Emphasis will be placed on analysis of neurons at the molecular level.

    Terms: Winter 2023

    Instructors: Cloutier, Jean-Francois; Ragsdale, David S; Kennedy, Timothy E; Fournier, Alyson Elise; Sossin, Wayne Steven; Ruthazer, Edward; Huang, Wei-Hsiang (Winter)

  • PARA 410 Environment and Infection (3 credits)

    Offered by: Parasitology (Agricultural & Environmental Sciences)

    Overview

    Parasitology : Infectious pathogens of humans and animals and their impact on the global environment are considered. The central tenet is that infectious pathogens are environmental risk factors. The course considers their impact on the human condition and juxtaposes the impact of control and treatment measures and environmental change.

    Terms: Winter 2023

    Instructors: Scott, Marilyn (Winter)

  • PATH 300 Human Disease (3 credits)

    Offered by: Pathology (Faculty of Science)

    Overview

    Pathology : Provides a fundamental understanding of the diseases prevalent in North America, for upper level students in the biological sciences. Includes: general responses of cells and organ systems to injury; assessment of individual diseases by relating the causes, symptoms, diagnosis, treatment and prevention to the primary biological abnormalities in each disorder.

    Terms: Winter 2023

    Instructors: Zorychta, Edith (Winter)

  • PHAR 390 Laboratory in Pharmacology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This course is a two-week all day practical laboratory course where students will have the opportunity to design their own experiments, write out the experimental lab reports and learn to trouble shoot on their own.

    Terms: Summer 2023

    Instructors: Munter, Lisa (Summer)

    • Restriction(s): Restricted to Pharmacology Honours students, or permission of instructor.

  • PHAR 503 Drug Discovery and Development 1 (3 credits) **

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Chemistry, mechanisms of action, and steps in drug discovery and development.

    Terms: Fall 2022

    Instructors: Munter, Lisa; Sharif Naeini, Reza; Meerovitch, Karen; Mooser, Vincent (Fall)

  • PHAR 504 Drug Discovery and Development 2 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Nobel Prize-winning discoveries as a basis for drug development.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

    • Winter

    • Prerequisites: PHAR 301 or PHAR 303; or permission of instructor

    • Restriction: U3 and graduate students. Students can register only with permission of coordinators.

  • PHAR 505 Structural Pharmacology (3 credits) **

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : The course will cover approaches widely used in the pharmaceuticals industry, such as drug target selection, structure determination and medicinal chemistry. The basics of structural biology will be taught in a very visual and interactive manner, with an emphasis on drug:target interactions and chemical principles relevant to drug design. By the end of the course, the students will become familiar with the structure-based drug discovery process and principles of molecular pharmacology.

    Terms: Fall 2022

    Instructors: Trempe, Jean-Francois; Corbeil, Christopher; Castagner, Bastien (Fall)

    • Prerequisite(s): PHAR 301, BIOC 311 or with permission of instructor

    • Restriction(s): Not open to students who have taken or are taking PHAR 503.

  • PHAR 508 Drug Discovery and Development 3 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : The design of biologically-relevant drug screens for molecular targets in a cell, tissue, and in vivo setting. Explore the use of stem cells and tissue-based disease models for the understanding of disease and for drug discovery. Situate modern pharmacology into broader medical and societal issues such as personalized medicine and the ethics associated with research.

    Terms: Winter 2023

    Instructors: Hebert, Terence; Clarke, Paul; Tanny, Jason (Winter)

    • Prerequisite(s): PHAR 301 (PHAR 503 or PHAR 505 are also highly recommended)

    • Restriction(s): Open to U3 students in the minor, major or honours program in Pharmacology.

    • Not open to students who have taken PHAR 558.

    • Assessment modalities- in class presentations and discussion, take-home exams and writing exercises.

  • PHAR 510 New Advances in Antimicrobial (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Overview on bacteria, insights into bacterial pathogenesis, an understanding of antibiotics, and new developments in antibacterial to beat antibiotic resistance.

    Terms: Winter 2023

    Instructors: Thanabalasuriar, Ajitha; Castagner, Bastien; Cuella Martin, Raquel (Winter)

    • Restrictions: Open to U3 students and above. Class capacity is first come first serve, after the first 15 students, the next 10 students priority will be given to MIMM and PHAR students. Not open to students who have taken or are taking MIMM 510.

  • PHAR 540 Advances in Industrial Biotechnology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Introduction to emerging technologies and research advances in biotechnologies. Topics include semisynthetic production of drugs and drug candidates through large-scale fermentation, next generation synthesis of DNA and whole genes, green toxicology, single-molecule diagnostics, orphan-drug re-purposing, and next- generation genomic analyses in drug development. Translational research, issues of entrepreneurship, sustainability, and ethics are also covered.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

    • Prerequisite: CHEM 222 (or equivalent) and BIOL 200 or CHEM 332

    • Restriction: U3 Students or higher. Not open to students who have taken or are taking CHEM 540.

  • PHAR 562 Neuropharmacology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Topics in pharmacology with an emphasis on molecular mechanisms of drug-action and cellular targets in the nervous system.

    Terms: Fall 2022

    Instructors: Bowie, Derek; Trempe, Jean-Francois; Leyton, Marco; McKinney, R. Anne; Stellwagen, David; Khoutorsky, Arkady; Multhaup, Gerhard; Munter, Lisa (Fall)

    • Fall

    • Prerequisite: PHAR 301 or with permission of instructor.

    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.

  • PHAR 563 Endocrine Pharmacology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This advanced course covers selected topics in pharmacology of reproductive, endocrine, and metabolic disorders.

    Terms: Fall 2022

    Instructors: Bernard, Daniel; Robaire, Bernard; Trasler, Jacquetta M (Fall)

    • Prerequisite: PHAR 301 or permission of the instructor(s)

    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.

    • Course material will be presented in the form of lectures and student-led presentations.

  • PHAR 565 Epigenetic Drugs and Targets (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This course covers therapeutics targeting epigenetic mechanisms. Although only a handful of epigenetic drugs are in widespread use, further development of such agents is a very active area of research as it has the potential to directly target aberrant gene expression. This course will examine both the current use and potential of epigenetic drugs in treatment of cancer, neurological diseases, immune disorders, and cardiovascular disease. The concept of epigenetics as mediating gene-environment interaction will also be discussed.

    Terms: Winter 2023

    Instructors: Tanny, Jason; Trasler, Jacquetta M; Szyf, Moshe (Winter)

    • Prerequisite(s): PHAR 301.

    • Restrictions: Not open to students who have taken or are taking HGEN 673.

  • PHGY 311 Channels, Synapses and Hormones (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system.

    Terms: Fall 2022

    Instructors: Cooper, Ellis; Sjostrom, Per Jesper; Krishnaswamy, Arjun; Sharif Naeini, Reza (Fall)

    • Fall

    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term

    • Prerequisite: PHGY 209 or permission of the instructor.

  • PHGY 312 Respiratory, Renal, and Cardiovascular Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level.

    Terms: Winter 2023

    Instructors: Hanrahan, John W; Martin, James G; Shrier, Alvin; Magder, Sheldon A (Winter)

    • Winter

    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term

    • Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor

  • PHGY 313 Blood, Gastrointestinal, and Immune Systems Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology.

    Terms: Winter 2023

    Instructors: Mandl, Judith; Pantopoulos, Konstantinos; Blank, Volker Manfred; Kokoeva, Maia; Vollrath, Melissa; Fritz, Jörg; Quail, Daniela (Winter)

    • Winter

    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term

    • Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor

  • PHGY 314 Integrative Neuroscience (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours.

    Terms: Fall 2022

    Instructors: Chacron, Maurice; Pack, Christopher; Shmuel, Amir; Vollrath, Melissa; Lomber, Stephen; Brandon, Mark; Krishna, Suresh (Fall)

    • Fall

    • 3 hours of lectures per week

    • Prerequisites: PHGY 209

  • PHGY 425 Analyzing Physiological Systems (3 credits) +

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : An introduction to quantitative analysis of physiological data, both to the mode of thinking and to a set of tools that allows accurate predictions of biological systems. Examples will range from oscillating genetic networks to understanding higher brain function. Modelling and data analysis through examples and exercises will be emphasized.

    Terms: Fall 2022

    Instructors: Cook, Erik; Glavinovic, Mladen I; Baker, Curtis L; Bashivan, Pouya (Fall)

  • PHGY 520 Ion Channels (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : A discussion of the principal theories and interesting new developments in the study of ion channels. Based on a textbook, computer exercises and critical reading and presentation of research papers. Topics include: Properties of voltage-and ligand-gated channels, single channel analysis, structure and function of ion channels.

    Terms: Fall 2022

    Instructors: Sharif Naeini, Reza; Ragsdale, David S; Shrier, Alvin; Hanrahan, John W; Seguela, Philippe; Bowie, Derek (Fall)

    • Winter

    • Offered in even numbered years

    • 1 1/2 hour lecture, 1 1/2 hour seminar

    • Prerequisite: PHGY 311

    • Priority to Graduate and Honours students; others by permission of instructors.

  • PHGY 524 Chronobiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : An introduction to the field of chronobiology. The aim is to provide basic instruction on different types of biological rhythms, with particular focus on circadian rhythms.

    Terms: Fall 2022

    Instructors: Cermakian, Nicolas; Bernard, Daniel; Storch, Kai-Florian (Fall)

  • PPHS 501 Population Health and Epidemiology (3 credits)

    Offered by: Epidemiology and Biostatistics (Faculty of Medicine and Health Sciences)

    Overview

    PPHS : This course presents concepts and methods of epidemiology at the introductory level. The use of epidemiologic methods for population and public health research and practice will be illustrated. A review of selected population health questions such as the HIV/AIDS epidemic, the cardiovascular disease epidemic, cigarette smoking, or screening for disease will be presented.

    Terms: Fall 2022

    Instructors: Banerjee, Ananya (Fall)

    • Restriction(s): Not open to students who have taken EPIB 501.

    • Course not open to students enrolled in Epidemiology or Public Health programs.

  • PSYC 302 The Psychology of Pain (3 credits)

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : An introduction to pain research and theory, with emphasis on the interactions of psychological, cultural and physiological factors in pain perception. The role of these factors in clinical pain and its management by pharmacological and non-pharmacological means will be discussed.

    Terms: Winter 2023

    Instructors: Mogil, Jeffrey (Winter)

    • Fall

    • 3 lectures

    • Prerequisite: any of the following: NSCI 201, PSYC 211, PSYC 212 or permission of instructor.

    • Restriction: Not open to students who are taking or have taken PSYC 505.

  • PSYC 305 Statistics for Experimental Design (3 credits) ***

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : An introduction to the design and analysis of experiments, including analysis of variance, planned and post hoc tests and a comparison of anova to correlational analysis.

    Terms: Fall 2022, Winter 2023, Summer 2023

    Instructors: Sajjad, Alia (Fall) Miocevic, Milica (Winter) Darainy, Mohammad (Summer)

    • Fall and Winter

    • Prerequisite: PSYC 204 or equivalent

    • This course is required of all students who propose to enter an Honours or Major program in Psychology

    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.

  • PSYC 311 Human Cognition and the Brain (3 credits)

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : The course is an introduction to the field studying how human cognitive processes, such as perception, attention, language, learning and memory, planning and organization, are related to brain processes. The material covered is primarily based on studies of the effects of different brain lesions on cognition and studies of brain activity in relation to cognitive processes with modern functional neuroimaging methods.

    Terms: Fall 2022

    Instructors: Brochu Barbeau, Elise; Hadid, Vanessa (Fall)

    • Fall

    • 2 lectures; 1 conference

  • PSYC 317 Genes and Behaviour (3 credits) ***

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : Focuses on current techniques employed to study which genes influence behaviour, and how they do so.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

  • PSYC 318 Behavioural Neuroscience 2 (3 credits) ***

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : The physiological bases of motivational states, with respect to feeding, drinking, sexual behaviour, drug use, and aggression. Physiological bases of learning and memory.

    Terms: Winter 2023

    Instructors: Britt, Jon (Winter)

  • PSYT 301 Issues in Drug Dependence (3 credits)

    Offered by: Psychiatry (Faculty of Science)

    Overview

    Psychiatry : The phenomenology and epidemiology of the use and abuse of alcohol, nicotine, opiates, stimulants, sedatives and psychotomimetic agents are discussed in relation to current theoretical and experimental issues. The perspective is multidisciplinary and the intention is to develop an understanding of the nature of the issues surrounding drug dependence.

    Terms: Fall 2022

    Instructors: Gratton, Alain; Rabin, Rachel (Fall)

  • PSYT 455 Neurochemistry (3 credits)

    Offered by: Psychiatry (Faculty of Science)

    Overview

    Psychiatry : Covers biochemical mechanisms underlying central nervous system function. Introduces basic neuroanatomy, CNS cell types and morphology, neuronal excitability, chemically mediated transmission, glial function. Biochemistry of specific neurotransmitters, endocrine effects on brain, brain energy metabolism and cerebral ischemia (stroke). With examples, where relevant, of biochemical processes disrupted in human CNS disease.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

  • PSYT 500 Advances: Neurobiology of Mental Disorders (3 credits)

    Offered by: Psychiatry (Faculty of Science)

    Overview

    Psychiatry : Current theories on the neurobiological basis of most well known mental disorders (e.g. schizophrenia, depression, anxiety, dementia). Methods and strategies in research on genetic, physiological and biochemical factors in mental illness will be discussed. Discussion will also focus on the rationale for present treatment approaches and on promising new approaches.

    Terms: Winter 2023

    Instructors: Wong, Tak Pan; Nagy, Corina; Beaulieu, Serge; Gobbi, Gabriella; Poirier, Judes; Brunet, Alain; Srivastava, Lalit K; Leyton, Marco; Paudel, Hemant K; Silveira, Patricia (Winter)

    • Winter

    • 3 hours

    • Prerequisite (Undergraduate): BIOC 212 and BIOC 311, or BIOC 312, or BIOL 200 and BIOL 201, or PHGY 311, or PSYC 308 and an upper-level biological science course with permission of the instructors, or equivalent. Basic knowledge of cellular and molecular biology is required.

    • Restriction: Open to U3 and graduate students only.

    • Restriction: Graduate Studies: strongly recommended for M.Sc. students in Psychiatry.

  • REDM 410 Writing Research Articles (3 credits)

    Offered by: Redpath Museum (Faculty of Science)

    Overview

    Redpath Museum : Students will learn about the scientific article, publishing in the sciences, and the benefits of writing for a wide audience. This course focuses on how to structure the Abstract, as well as the Introduction and Discussion section of the full manuscript, and on editing techniques.

    Terms: This course is not scheduled for the 2022-2023 academic year.

    Instructors: There are no professors associated with this course for the 2022-2023 academic year.

    • Prerequisite: 24 credits of 200/300-level Science courses.

    • Restriction: This is an advanced course and permission of the instructor is required. To obtain permission, students should email the instructor, linda.cooper [at] mcgill.ca. Not open to students who are taking or have taken REDM 399.

Note:
* Students may take either ANAT 458 or BIOC 458.
**Students may take either PHAR 503 or PHAR 505.
*** Access to these courses is not guaranteed
+ Open to students who have the prerequisites
++ Access to these courses is not guaranteed. Open to students who have the prerequisites.

Faculty of Science—2022-2023 (last updated Aug. 24, 2022) (disclaimer)
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